New York, NY7 Active Studies

Substance Use Disorder Clinical Trials in New York, NY

Find 7 actively recruiting substance use disorder clinical trials in New York, NY. Connect with local research sites and explore new treatment options.

7
Active Trials
5
Sponsors
1,110
Enrolling

Recruiting Substance Use Disorder Studies in New York

RecruitingNew York, NYNCT05033028

Smartphones for Opiate Addiction Recovery

Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use du...

225 participants
NYU Langone Health
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RecruitingNew York, NYNCT06051890

Assessing Optimal XRB Initiation Points in Jail

This application describes a 3-year, randomized controlled trial. Eligible, consenting adults (N=200) with existing sublingual buprenorphine (SLB) prescriptions who enter Middlesex County House of Cor...

200 participants
NYU Langone Health
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RecruitingNew York, NYNCT06548490

GLP-1R Agonist Treatment for Opioid Use Disorder

The goal of this clinical trial is to learn if semaglutide can reduce illicit opioid use in adults in outpatient treatment for opioid use disorder, and who are receiving either buprenorphine or methad...

200 participants
Milton S. Hershey Medical Center
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RecruitingNew York, NYNCT05011266

Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder

This study will evaluate the effectiveness of a new pharmacological approach to increase efficacy of treatment with extended release naltrexone (XR-naltrexone) for individuals with opioid use disorder...

180 participants
New York State Psychiatric Institute
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RecruitingNew York, NYNCT05589181

High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)

This project, involving two distinct clinical trials, tests whether induction to a higher than currently recommended buprenorphine (BUP) induction dose is safe and can improve the proportion of patien...

140 participants
Rutgers, The State University of New Jersey
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RecruitingNew York, NYNCT06496750

Ketamine for Methamphetamine Use Disorder

This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week rando...

120 participants
University of Texas Southwestern Medical Center
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RecruitingNew York, NYNCT04458545

Clinical Trials of Multivalent Opioid Vaccine Components

Currently, abuse of prescription opioid analgesics and heroin is a serious problem in the U.S. Although several medications, including methadone, buprenorphine, and naltrexone, are available and effec...

45 participants
New York State Psychiatric Institute
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About Substance Use Disorder Clinical Trials in New York

Substance use disorder is a condition where the use of substances leads to health issues, disability, and failure to meet responsibilities. It encompasses alcohol, opioid, stimulant, and other drug addictions. Treatment includes behavioral therapy, medication-assisted treatment, and support programs.

There are currently 7 substance use disorder clinical trials recruiting participants in New York, NY. These studies are seeking a combined 1,110 participants. Research is being sponsored by NYU Langone Health, Milton S. Hershey Medical Center, New York State Psychiatric Institute and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Substance Use Disorder Clinical Trials in New York — FAQ

Are there substance use disorder clinical trials in New York?

Yes, there are 7 substance use disorder clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What substance use disorder treatments are being tested?

The 7 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for substance use disorder.

Data updated March 2, 2026 from ClinicalTrials.gov