Orange, CANCT06028828Now EnrollingIRB Ready

Allogeneic Hematopoietic Stem Cell Transplantation Clinical Trial in Orange, CA

Access cutting-edge allogeneic hematopoietic stem cell transplantation treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Irvine

Quick Self-Assessment

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Expert Care in Orange

Access allogeneic hematopoietic stem cell transplantation specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related allogeneic hematopoietic stem cell transplantation treatment provided free

Apply for This Orange Location

Check if you qualify for this allogeneic hematopoietic stem cell transplantation clinical trial in Orange, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Allogeneic Hematopoietic Stem Cell Transplantation Study in Orange

This is a prospective, single-arm, phase II study. Patients will be treated with an allogeneic stem cell transplantation (AHSCT) using fludarabine, melphalan and total body irradiation (TBI) conditioning with different melphalan and TBI doses based on patient- and disease-related risk.

Sponsor: University of California, Irvine

Who Can Participate

Inclusion Criteria

Male or female aged 18-70 years
Diagnosis of AML, ALL, MDS, CML, NHL, HD, CLL requiring AHSCT
Has an HLA-matched related (MRD), HLA-matched unrelated (MUD), haploidentical (HAPLO) or 1-Ag mismatched unrelated donor (MMUD)
Karnofsky performance \>70%
Adequate major organ system function as demonstrated by:
Serum creatinine clearance equal or more than 50 ml/min (calculated with Cockroft-Gault formula).
Bilirubin equal or less than 1.5 mg/dl except for Gilbert's disease. ALT or AST equal or less than 200 IU/ml for adults. Conjugated (direct) bilirubin less than 2x upper limit of normal.
Left ventricular ejection fraction equal or greater than 40%.
Diffusing capacity for carbon monoxide (DLCO) equal or greater than 50% predicted corrected for hemoglobin.
Ability to understand and the willingness to sign a written informed consent. a. Both men and women and members of all races and ethnic groups are eligible for this trial. Non-English speaking, deaf, hard of hearing and illiterate individuals are eligible for this trial.

Exclusion Criteria

Inability to comply with medical recommendations or follow-up
Active/uncontrolled bacterial or viral infection (PI is the final arbiter of this criterion.)
Has active CNS or ocular disease involvement within 3 months
Patients with primary CNS lymphoma
Patients who require modifications of the conditional regimen

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT06028828) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Allogeneic Hematopoietic Stem Cell Transplantation Treatment Options in Orange, CA

If you're searching for allogeneic hematopoietic stem cell transplantation treatment options in Orange, CA, this clinical trial (NCT06028828) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced allogeneic hematopoietic stem cell transplantation specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all allogeneic hematopoietic stem cell transplantation clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA