Little Rock, ARNCT07494305Now EnrollingIRB Ready

Bipolar I Disorder Clinical Trial in Little Rock, AR

Access cutting-edge bipolar i disorder treatment through this clinical trial at a research site in Little Rock. Study-provided care at no cost to qualified participants.

Sponsored by LB Pharmaceuticals Inc.

Quick Self-Assessment

See if you qualify for this Little Rock location

Preparing your pre-screening questions…

Expert Care in Little Rock

Access bipolar i disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related bipolar i disorder treatment provided free

Apply for This Little Rock Location

Check if you qualify for this bipolar i disorder clinical trial in Little Rock, AR

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Little Rock

    Convenient for AR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Little Rock site if eligible
  4. 4Begin participation

About This Bipolar I Disorder Study in Little Rock

Phase II study for patients with Bipolar 1 Disorder experiencing major depressive episode. Patient eligible for enrollment will be randomized (like flipping a coin) to either active drug (LB-102 or placebo). Treatment is for 6 weeks.

Sponsor: LB Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Sign IRB approved ICF, Stable living environment
Diagnosis of Bipolar1 disorder defined by criteria in the DSM 5 and currently experiencing a MDE without psychotic or mixed features, and supported by the SCID 5 CT
Currently experiencing an MDE that began at least 4 weeks but no more than 18 months prior to randomization
Currently treated in an out-patient environment
MADRS 10 total score ≥24 at both Screening and Baseline with a difference of \<20% in scores between visits.
Clinical Global Impression Scale, Bipolar Version Severity of Illness scale (CGI BP S) depression score ≥4 at both Screening and Baseline.
YMRS total score ≤12 at both Screening and Baseline.
Good physical health
BMI of ≥18 and ≤40 kg/m2.
Eligibility confirmed centrally for the severity, diagnosis, and treatment history by the SAFER interview.

Exclusion Criteria

Sexually active woman of childbearing potential and male who are not practicing 2 different methods of birth control or woman who is currently breast feeding
History of non-response to 2 adequate medication trials for depressive symptoms
Improvement of ≥20% in MADRS 10 total score between the screening and baseline assessments
Have bipolar disorder with mixed features or considered as rapid cyclers
Plan to initiate formal cognitive or behavioral therapy, systematic psychotherapy during the study, or plan to initiate such therapy during the study
History of disorders other than bipolar disorder, confirmed by previous psychiatric evaluation or the DSM 5 within 12 months prior to Screening
Experience of hallucinations, delusions, or any other psychotic symptomatology in the current MDE attributable to a primary DSM 5 diagnosis other than bipolar disorder.
Hospitalized for mania associated with Bipolar I Disorder within 30 days prior to Screening. Any previous manic phase must have completely resolved before enrollment in the study.
Significant risk for suicidal behavior during the study as determined by the Investigator's clinical assessment
Hypo or hyperthyroidism
Insulin dependent diabetes
Uncontrolled hypertension
Known significant cardiac disease
Laboratory results outside the defined protocol ranges
Clinically significant abnormal ECG findings
Received electroconvulsive therapy (ECT) within 90 days prior to Screening.
Received Transcranial Magnetic Stimulation within 90 days prior to Screening
Currently taking prohibited medications as defined in the protocol
History of non-response and/or responded only to ketamine, ECT or vagus nerve stimulation
Received GLP-1 within 30 of screening
History of organ disease that in the opinion of the PI would not make the patient eligible for participation

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Little Rock?

Yes, this clinical trial (NCT07494305) has an active research site in Little Rock, AR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Bipolar I Disorder Treatment Options in Little Rock, AR

If you're searching for bipolar i disorder treatment options in Little Rock, AR, this clinical trial (NCT07494305) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Little Rock research site is actively enrolling participants for this clinical trial. You'll receive care from experienced bipolar i disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all bipolar i disorder clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Little Rock, AR