Cleveland, OHNCT06101069Now EnrollingIRB Ready

Brain Tumor Clinical Trial in Cleveland, OH

Access cutting-edge brain tumor treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by Case Comprehensive Cancer Center

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Expert Care in Cleveland

Access brain tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related brain tumor treatment provided free

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Check if you qualify for this brain tumor clinical trial in Cleveland, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Brain Tumor Study in Cleveland

The purpose of this study is to discover the potential convenience and ease of using a Magnetic Resonance Imaging (MRI) technique, named Magnetic Resonance Fingerprinting (or MRF), to achieve high-quality images within a short scan time of 5 min for viewing the entire brain. This is an advanced quantitative assessment of brain tissues. This method is being applied with IVIM MRI to be able to tell the difference between a brain with radiation necrosis and a brain with tumor recurrence. Participants will consist of individuals who have received radiation therapy in the past and were diagnosed with radiation necrosis, individuals with recurrent tumors, individuals with previously untreated tumors, and healthy individuals who have no brain diseases and have not had radiation treatment to the brain. Participants will undergo an MRI scan at a one-time research study visit; no extra tests or procedures will be required for this research study. The primary objectives of this study are: * To demonstrate the clinical feasibility of combining MRF with state-of-the-art parallel imaging techniques to achieve high-resolution quantitative imaging within a reasonable scan time of 5 min for whole brain coverage. * To apply the developed quantitative approach in combination with IVIM MRI for differentiation of tumor recurrence and radiation necrosis. * To investigate the effect of radiation dose on the development of radiation necrosis and tumor recurrence.

Sponsor: Case Comprehensive Cancer Center

Who Can Participate

Inclusion Criteria

for Healthy Participants:
Ages 18 - 60
No history of cerebrovascular disease
No cognitive impairments
Able to provide informed consent Inclusion Criteria for Participants with Brain Tumors:
Biopsy-proven cases of developed recurrent tumor or radiation necrosis, OR
a. PET identified with developed recurrent tumor or radiation necrosis. OR
b. Highly suspicious case with developed recurrent tumor or radiation necrosis confirmed by tumor board, attending physician or surgeon.
ECOG performance status 0-2.
Life expectancy \> 6 months.
Participant with other sites of extracranial metastatic disease or any prior or current systemic therapies will be considered and evaluated by the investigators of the study on a subject basis. Inclusion Criteria for Participants with Brain Metastases or Primary Gliomas:
Radiology identified with developed primary gliomas tumor or brain metastases, OR
a. PET identified with developed gliomas tumor or brain metastases, OR
b. Highly suspicious case with developed gliomas tumor or brain metastases confirmed by tumor board
Participants must not have received prior radiation or surgical treatment for brain metastases or primary glioma.
Age: 18 years and over
ECOG performance status 0-2
Life expectancy \> 6 months.
Participant with other sites of extracranial metastatic disease or any prior or current systemic therapies will be considered and evaluated by the investigators of the study on a subject basis. Inclusion Criteria for Participants with Meningiomas:
Radiology identified with resectable meningioma
Participants have no prior radiation or surgical treatment for brain lesions
Age: 18 years or older
ECOG performance status 0-2
Life expectancy \> 6 months.
Participants with other sites of extracranial metastatic disease or any prior or current systemic therapies will be considered and evaluated by the investigators of the study on a subject basis.

Exclusion Criteria

Pregnant women OR lactating women
Participants with ferromagnetic or otherwise non-MRI compatible aneurysm clips.
Participants who cannot go into the MRI scanner due to metal implants and other medical conditions.
The presence of an implanted medical device that is not MRI-compatible, including, but not limited to: pacemaker, defibrillator.
Participants with contraindications for MRI due to embedded foreign metallic objects such as bullets, shrapnel, metalwork fragments, or other metallic material.
Known history of severe claustrophobia.
Participants unable to lay still in the scanner for 30 minutes at a time.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT06101069) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Brain Tumor Treatment Options in Cleveland, OH

If you're searching for brain tumor treatment options in Cleveland, OH, this clinical trial (NCT06101069) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced brain tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all brain tumor clinical trials near you to find additional studies recruiting in your area.

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