Minneapolis, MNNCT05881863Now EnrollingIRB Ready

Central Airway Obstruction Clinical Trial in Minneapolis, MN

Access cutting-edge central airway obstruction treatment through this clinical trial at a research site in Minneapolis. Study-provided care at no cost to qualified participants.

Sponsored by University of Minnesota

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Expert Care in Minneapolis

Access central airway obstruction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related central airway obstruction treatment provided free

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Check if you qualify for this central airway obstruction clinical trial in Minneapolis, MN

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Why Participate?

  • No-Cost Study Care

  • Local to Minneapolis

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Minneapolis site if eligible
  4. 4Begin participation

About This Central Airway Obstruction Study in Minneapolis

Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation). However, this method carries with it an increased risk for airway fire - a surgical fire that occurs in a patient's airway and could also include a fire in the attached breathing circuit. To decrease the risk of airway fire during mechanical ventilation with an endotracheal tube, the concentration of inspired oxygen (FiO2) is set below 40% while waiting for end tidal oxygen concentration (EtO2) to fall below 40% prior to starting thermal ablation. There is no published literature describing O2 concentration within the airways (AiO2) during jet ventilation with rigid bronchoscopy. The co-investigators of this study have recently collected data on AiO2 during rigid bronchoscopy using manual low frequency jet ventilation/high frequency jet ventilation with a period of apnea. The intent of this study is to measure the time taken for the central airway oxygen concentration to drop from 90 to 40% when the "laser mode" is activated on the Monsoon jet ventilator. Ventilation is continued during "laser mode."

Sponsor: University of Minnesota

Who Can Participate

Inclusion Criteria

Patients undergoing rigid bronchoscopy for treatment of central airway obstruction at FV UMMC will be identified.
18 years or older
Need rigid bronchoscopy as pre-determined by the interventional pulmonologist

Exclusion Criteria

Refusal to sign consent
Pregnant patients
Hemodynamic instability defined as continuous infusion of medication in order to support blood pressure and/or heart rate/rhythm
Respiratory instability defined as SpO2\<90% with \>90% supplemental oxygen.
Ineligible for rigid bronchoscopic intubation
Latex allergy
Evidence of fistulous airway
Active Bronchopleural fistula

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Minneapolis?

Yes, this clinical trial (NCT05881863) has an active research site in Minneapolis, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Central Airway Obstruction Treatment Options in Minneapolis, MN

If you're searching for central airway obstruction treatment options in Minneapolis, MN, this clinical trial (NCT05881863) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Minneapolis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced central airway obstruction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all central airway obstruction clinical trials near you to find additional studies recruiting in your area.

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