Chicago, ILNCT07434492Now EnrollingIRB Ready

Cerebral Palsy Clinical Trial in Chicago, IL

Access cutting-edge cerebral palsy treatment through this phase 2 clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by Shirley Ryan AbilityLab

Quick Self-Assessment

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Expert Care in Chicago

Access cerebral palsy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cerebral palsy treatment provided free

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Check if you qualify for this cerebral palsy clinical trial in Chicago, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Cerebral Palsy Study in Chicago

This is an intervention study to investigate the impact of a smart ankle-foot orthosis (AFO) on mobility outcomes in children with Cerebral Palsy. Participants will complete a three phase protocol including 6-weeks of at home training with the smart AFO. Participants will also have the option to participate in a randomized control trial to investigate the impact of 5-Azacitidine combined with the smart AFO to further effect mobility outcomes.

Sponsor: Shirley Ryan AbilityLab

Who Can Participate

Inclusion Criteria

Diagnosis of cerebral palsy classified as Gross Motor Function Classification System (GMFCS) levels I to III
Between 8 and 17 years and 8 months of age at the time of enrollment/consent. Participants that will turn 18 during the course of the study will not be included as pausing the at-home protocol until re-consenting is possible could interfere with intervention results.
Stable medical condition as determined by the investigator.
Adequate caregiver support to be able to participate in training and assessment sessions for the duration of the study, at the discretion of the PI.
Height/weight/BMI between the 5th - 95th percentile of children with cerebral palsy
Able to walk for at least 6 minutes (assisted or unassisted)
Able to understand and follow simple directions
Able to safely fit into a device configuration and tolerate assistance without knee hyperextension while walking
At least 20 degrees of passive ankle plantar flexion range of motion
Physician approval for participation

Exclusion Criteria

Knee extension or ankle dorsiflexion contractures greater than 15 degrees
Immunodeficiency or hematologic condition
Allergy to AZA or mannitol
Plans to receive a vaccine within 30 days of the planned AZA or placebo injection to take place at week 5
Orthopedic surgery on the lower limbs completed in the prior 12 months
New implanted device (e.g., baclofen pump) and/or active intrathecal medication titration that may affect muscle spasticity
Botulinum toxin treatment within 3 months preceding enrollment unless given approval by the study physician
Severe osteoporosis unless given approval by the study physician
Current enrollment in a conflicting research study
Any other health condition or diagnosis not listed above that may put the participant at risk as determined by the PI or study physician

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT07434492) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Cerebral Palsy Treatment Options in Chicago, IL

If you're searching for cerebral palsy treatment options in Chicago, IL, this clinical trial (NCT07434492) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced cerebral palsy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cerebral palsy clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Chicago, IL