Philadelphia, PANCT06914557Now EnrollingIRB Ready

CIPN - Chemotherapy-Induced Peripheral Neuropathy Clinical Trial in Philadelphia, PA

Access cutting-edge cipn - chemotherapy-induced peripheral neuropathy treatment through this phase 2 clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by Fox Chase Cancer Center

Quick Self-Assessment

See if you qualify for this Philadelphia location

Preparing your pre-screening questions…

Expert Care in Philadelphia

Access cipn - chemotherapy-induced peripheral neuropathy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related cipn - chemotherapy-induced peripheral neuropathy treatment provided free

Apply for This Philadelphia Location

Check if you qualify for this cipn - chemotherapy-induced peripheral neuropathy clinical trial in Philadelphia, PA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This CIPN - Chemotherapy-Induced Peripheral Neuropathy Study in Philadelphia

The investigators hypothesize that Scrambler therapy with duloxetine, compared to duloxetine-based usual care, will result in greater improvement in CIPN as measured by the BPI-Short Form. In addition, the investigators will further assess pain using the EORTC CIPN-20 and determine whether Scrambler therapy results in improved levels of function as measured with the PDQ, and a decreased need for opioid medications. Our primary objective is to investigate whether Scrambler therapy with duloxetine is superior to duloxetine-based usual care in achieving at least a 50% reduction in pain scores, when comparing the cross-sectionally measured "average" pain score at day 35 to the cross-sectionally measured "average" pain score at baseline.

Sponsor: Fox Chase Cancer Center

Who Can Participate

Inclusion Criteria

Persons aged 18 years or older with cancer
Eastern Cooperative Oncology Group 0-2
At least a 4/10 average pain score prior to treatment
At least CTCAE version 5.0 grade 2 neuropathies.
Diagnosed CIPN based on chart review or oncologist diagnosis; will allow pre-existing diabetic neuropathy if symptoms are changing or worsening after chemotherapy.
Score of at least 4 on the Douleur-Neuropathique-en-4 Questions (DN4) questionnaire
Patients must have discontinued neurotoxic chemotherapy within the last 3 months with no additional therapy planned for the next 6 months after initiation of CIPN treatment.
Patients must be on duloxetine at least 30 mg po daily for at least 4 weeks prior to study initiation
Patients must be able to provide informed written consent.

Exclusion Criteria

Children or adolescents
Pregnant or nursing patients
Presence of an implantable life supporting medical device or implantable drug delivery system
Patients with severe skin conditions preventing the proper application of electrodes
Patients currently on monoamine oxidase inhibitors MAOIs.
Patients currently receiving gabapentin who are unable to be weaned off for other medical reasons (ST requires tapering gabapentin).
Patients with a symptomatic neuropathy from any type of nerve compression (e.g. carpal tunnel or tarsal tunnel, radiculopathy, spinal stenosis, or brachial plexopathy)
Patients with leptomeningeal carcinomatosis- treated/stable brain metastases are allowed
Patients with severe depression, suicidal ideation, bipolar disease, alcohol abuse, a major eating disorder
Patients with uncontrolled epilepsy.
Patients who have previously attempted or undergone Scrambler therapy.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT06914557) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

CIPN - Chemotherapy-Induced Peripheral Neuropathy Treatment Options in Philadelphia, PA

If you're searching for cipn - chemotherapy-induced peripheral neuropathy treatment options in Philadelphia, PA, this clinical trial (NCT06914557) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced cipn - chemotherapy-induced peripheral neuropathy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all cipn - chemotherapy-induced peripheral neuropathy clinical trials near you to find additional studies recruiting in your area.

More Pulmonary Embolism Trials in Philadelphia, PA

See all pulmonary embolism clinical trials recruiting in Philadelphia — not just this study.

Browse Pulmonary Embolism Trials in Philadelphia →

Ready to Join in Philadelphia?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Philadelphia, PA