Boston, MANCT07013591Now EnrollingIRB Ready

Coronary Artery Bypass Graft Clinical Trial in Boston, MA

Access cutting-edge coronary artery bypass graft treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Brigham and Women's Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access coronary artery bypass graft specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related coronary artery bypass graft treatment provided free

Apply for This Boston Location

Check if you qualify for this coronary artery bypass graft clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Coronary Artery Bypass Graft Study in Boston

The investigators will perform a phase 2a, randomized, double-blind, placebo-controlled clinical trial in adult patients undergoing elective coronary artery bypass grafting (CABG) surgery to investigate the effects of oral nicotinamide mononucleotide (NMN) administration on myocardial NAD+ concentrations and on postoperative markers of myocardial and kidney injury.

Sponsor: Brigham and Women's Hospital

Who Can Participate

Inclusion Criteria

Age ≥18 years
Scheduled to undergo elective isolated CABG surgery with cardiopulmonary bypass (CPB)
At increased risk of postoperative complications based on ≥1 of the following:
Age ≥65 years
eGFR \<45 ml/min/1.73m2
Documented history of congestive heart failure or left ventricular ejection fraction (LVEF) ≤40% within 6 months before surgery
Diabetes mellitus and urine albumin-to-creatinine ratio \>30 mg/g creatinine
Peripheral arterial disease
Anemia, defined as hemoglobin \<10 g/dl
Prior cardiac surgery

Exclusion Criteria

Any of the following laboratory abnormalities at the time of screening:
ALT \>3-fold the upper limit of normal
eGFR \<30 ml/min/1.73m2 or ESKD on dialysis
Hemoglobin \<8 g/dl
History of gastric bypass or malabsorption
Active alcohol or illicit substance use in the prior 6 months
Participation in an investigational trial to evaluate pharmaceuticals or biologics within the past 3 months or 5 half-lives, whichever is shorter
Pregnant or breast-feeding
Unwillingness to use contraception while taking study drug and for 8 weeks after the last dose for women of reproductive age or non-sterilized male participants who are sexually active with a female partner of childbearing potential
Current use of niacin \>100 mg/day or NMN, nicotinamide, or nicotinamide riboside at any dose
Conflict with other research studies
Any condition which, in the judgement of the investigator, might increase the risk to the participant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07013591) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Coronary Artery Bypass Graft Treatment Options in Boston, MA

If you're searching for coronary artery bypass graft treatment options in Boston, MA, this clinical trial (NCT07013591) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced coronary artery bypass graft specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all coronary artery bypass graft clinical trials near you to find additional studies recruiting in your area.

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