Boston, MANCT07082998Now EnrollingIRB Ready

Depression Disorders Clinical Trial in Boston, MA

Access cutting-edge depression disorders treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access depression disorders specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related depression disorders treatment provided free

Apply for This Boston Location

Check if you qualify for this depression disorders clinical trial in Boston, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Depression Disorders Study in Boston

This project explores whether heated yoga, sauna, and a mindfulness app reduce depressive symptoms

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

adults (18-65 years old)
Ability to provide informed consent
English language proficiency
PHQ-9 score \> 10, indicating at least moderate depressive symptoms 21
Must have filled out the waiver for the community-based partners prior to enrolling in the study\
Individuals of childbearing potential must use an acceptable form of birth control
(if applicable) willingness to keep psychiatric medications and psychotherapy stable throughout the course of the study
Must be able to access mindfulness app on a device (i.e., smartphone, iPad, etc.)
Can travel to Breathe in Harvard Square and at least one Restore location (i.e., Hingham, Somerville, Dedham, Newton, Lynnfield)

Exclusion Criteria

Pregnant or planning to become pregnant
Breast feeding
Active suicidal thinking (i.e., PHQ-9 item 9 ≥1 and a positive response to C-SSRS screener items 3, 4, 5, or 6)
Active eating disorders or substance use disorders within the past 12 months, as per the MINI
Primary OCD or PTSD, as per the MINI
History of bipolar disorder, psychotic disorders, as per the MINI
≥25% drop in PHQ-9 score from screen to baseline
Under the influence or withdrawal of drugs or alcohol
Positive urine toxicology screen due to illicit drug use or other exclusionary medications. (Potential false positives will be addressed on a case-by-case basis at the discretion of the PI or designee)
have had a bone fracture or joint surgery in the past 6 months
not able to walk freely or without difficulty
any serious, unstable medical condition as determined by the revised Physical Activity Readiness Questionnaire (PAR-Q+) and do not have approval from their treating physician (we will check in with treating physician in the event that participants endorse any item on the PAR-Q+)
participants must have a healthcare provider who they could contact if they needed medical care, such as a primary care doctor, a counselor, a psychiatrist, a nurse practitioner, or a clinic that you go to.
Significant exposure to heated yoga classes in the past 3 months (i.e., more than 6 classes)
Significant exposure to sauna sessions in the past 3 months (i.e., more than 6 sessions)
Significant exposure to mindfulness app in the past 3 months (i.e., more than 6 uses of the app)
are on medications that make dehydration more likely (e.g., lithium, antipsychotics, insulin-dependent) diuretics, barbiturates, b-blockers, anticholinergics, current ETOH acute intoxication, reduced ability to sweat, hemophilia, pacemaker (magnets used to assemble saunas can interrupt the pacer)
antidepressant or psychiatric medications that are initiated less than 8 weeks or a dose change less than 4 weeks prior to screening visit
psychotherapy that has been initiated within the past 3 months
psychiatric hospitalization within the past year
diagnosed with any neurological disorders that would impact participation or make participation unsafe
are currently in active ketamine, Electroconvulsive therapy, or Transcranial Magnetic Stimulation treatments
are unable to follow the study procedures (e.g., not able to travel to the heated yoga or sauna studios)
A subject who in the opinion of the Principal Investigator would not be able to safely complete the study or would jeopardize study integrity

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07082998) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Depression Disorders Treatment Options in Boston, MA

If you're searching for depression disorders treatment options in Boston, MA, this clinical trial (NCT07082998) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced depression disorders specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all depression disorders clinical trials near you to find additional studies recruiting in your area.

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