Needham, MANCT07195721Now EnrollingIRB Ready

Depression - Major Depressive Disorder Clinical Trial in Needham, MA

Access cutting-edge depression - major depressive disorder treatment through this clinical trial at a research site in Needham. Study-provided care at no cost to qualified participants.

Sponsored by Boston Sight

Quick Self-Assessment

See if you qualify for this Needham location

Preparing your pre-screening questions…

Expert Care in Needham

Access depression - major depressive disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related depression - major depressive disorder treatment provided free

Apply for This Needham Location

Check if you qualify for this depression - major depressive disorder clinical trial in Needham, MA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Needham

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Needham site if eligible
  4. 4Begin participation

About This Depression - Major Depressive Disorder Study in Needham

The goal of this prospective clinical trial is to evaluate the effect that prosthetic replacement of the ocular surface ecosystem (PROSE, BostonSight, Needham MA) treatment may have on mental health, particularly affective mood disorders. Correlation between changes in mental health and ocular symptom improvement and/or visual function improvement will be evaluated.

Sponsor: Boston Sight

Who Can Participate

Inclusion Criteria

Written Informed Consent has been obtained prior to any study-related procedures taking place.
Subject is Male or Female, 18 years of age or older prior to the initial visit.
Patient is proceeding with a PROSE or scleral lens consultation in one or both eyes for the primary diagnosis of ocular surface disease, including but not limited to Ocular Graft vs Host Disease, Keratoconjunctivitis Sicca, Dry eye, Sjogren's Disease, Rheumatologic ocular surface disease, Exposure Keratitis, Limbal Stem Cell Deficiency, Steven Johnson Syndrome, Mucous Membrane Pemphigoid (Ocular Cicatricial Pemphigoid), Atopic Keratoconjunctivitis, Chemical injury.
Baseline PHQ-9 score \> 4
Baseline OSDI score of 13 or greater
In the opinion of the investigator, the subject can follow study instructions, complete all study procedures and visits
Is able to understand the English language in verbal and written interactions -

Exclusion Criteria

Is currently participating in any other type of eye-related clinical research study that in the opinion of the investigator would interfere with the study
Is pregnant or nursing as reported by the subject.
Has a condition or is in a situation which, in the investigator's opinion, may put the subject at significant risk, may confound study outcomes, or may significantly interfere with the subject's participation in the study.
Recently started medication or other therapeutic treatments for affective mood disorders (such as depression) within the last 8 weeks.
Recently started new treatment for ocular surface disease, including but not limited to topical medicated drops, procedures, punctal plugs within the last 8 weeks.
Ocular surgery within the last 8 weeks
Planned ocular surgery within the study period
Has a known allergy to topical ophthalmic sodium fluorescein dye
Has a known intolerance to topical ophthalmic normal saline
Neurotrophic Keratitis
Corneal ectasia
PROSE or scleral lens wearer within the last 1 year prior to Visit 1 \[subjects who have solely tried a PROSE or scleral lens in an office setting consultation (and were never dispensed for home use) ARE eligible for enrollment, regardless of whether it occurred in the last year\]
Is an employee of BostonSight or an employee of a site performing the study -

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Needham?

Yes, this clinical trial (NCT07195721) has an active research site in Needham, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Depression - Major Depressive Disorder Treatment Options in Needham, MA

If you're searching for depression - major depressive disorder treatment options in Needham, MA, this clinical trial (NCT07195721) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Needham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced depression - major depressive disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all depression - major depressive disorder clinical trials near you to find additional studies recruiting in your area.

More Depression Trials in Needham, MA

See all depression clinical trials recruiting in Needham — not just this study.

Browse Depression Trials in Needham →

Browse More Trials by Condition

Depression TrialsMajor Depressive Disorder TrialsAll Conditions →

Ready to Join in Needham?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Needham, MA