Oklahoma City, OKNCT05174052Now EnrollingIRB Ready

Diabetes Mellitus Clinical Trial in Oklahoma City, OK

Access cutting-edge diabetes mellitus treatment through this clinical trial at a research site in Oklahoma City. Study-provided care at no cost to qualified participants.

Sponsored by University of Oklahoma

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Expert Care in Oklahoma City

Access diabetes mellitus specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related diabetes mellitus treatment provided free

Apply for This Oklahoma City Location

Check if you qualify for this diabetes mellitus clinical trial in Oklahoma City, OK

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Oklahoma City

    Convenient for OK residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Oklahoma City site if eligible
  4. 4Begin participation

About This Diabetes Mellitus Study in Oklahoma City

The study will investigate the effect of Dapagliflozin on atrial fibrillation (AF) burden. AF burden will be defined as the percent of time spent in AF over a 2-week period, assessed by noninvasive continuous heart rhythm monitoring at baseline and at 3 months, quality of life (QOL) and validated echocardiographic indices of atrial myopathy. This knowledge will enable us to study the therapeutic potential of SGLT2i as a novel adjunct treatment for patients with DM and AF. Patients with paroxysmal AF (AF that terminates spontaneously or with intervention within seven days of onset) and DM and randomize them to Dapagliflozin or placebo. Continuous heart rhythm monitoring patch for AF burden will be used, measure of QOL with the help of AF Effect on Quality-of-life survey and perform an echocardiogram with measurement of left atrial volume index, left atrial strain and atrial tissue dopplers. All measurements will be performed at baseline and at study completion. The central hypothesis is that SGLT2i will lead to reduced AF burden that will translate into improvement in QOL, and the underlying mechanism is improvement in atrial myopathy.

Sponsor: University of Oklahoma

Who Can Participate

Inclusion Criteria

Diagnosed with DM
Paroxysmal AF

Exclusion Criteria

Symptoms of hypotension or systolic blood pressure \<90mmHg,
Severe renal impairment with eGFR\<30mL/minute/1.73m2,
History of lower limb amputation,
Hypersensitivity to Dapagliflozin,
Currently taking any SGLT2i,
Currently taking anti-arrhythmic drugs
Undergoing catheter ablation will be excluded

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Oklahoma City?

Yes, this clinical trial (NCT05174052) has an active research site in Oklahoma City, OK that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Diabetes Mellitus Treatment Options in Oklahoma City, OK

If you're searching for diabetes mellitus treatment options in Oklahoma City, OK, this clinical trial (NCT05174052) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Oklahoma City research site is actively enrolling participants for this clinical trial. You'll receive care from experienced diabetes mellitus specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all diabetes mellitus clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Oklahoma City, OK