Ann Arbor, MINCT06044285Now EnrollingIRB Ready

Food Addiction Clinical Trial in Ann Arbor, MI

Access cutting-edge food addiction treatment through this clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by University of Michigan

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Expert Care in Ann Arbor

Access food addiction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related food addiction treatment provided free

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Check if you qualify for this food addiction clinical trial in Ann Arbor, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Food Addiction Study in Ann Arbor

This study experimentally investigates whether a reduction in ultra-processed (UP) food intake (1) causes aversive withdrawal symptoms in humans, (2) increases the motivational salience of UP food cues and, if so, (3) whether these factors undermine the ability to adhere to a low-UP diet. The following aims and hypotheses are tested: Aim 1: To investigate whether aversive physical, cognitive, and affective withdrawal symptoms emerge in response to reduced UP food intake compared to a high-UP diet, and whether this predicts failure to adhere to a low-UP diet. H1a: Reducing UP food intake will result in aversive physical, cognitive, and affective withdrawal symptoms, as indicated by 1) ecological momentary assessment (EMA) reports of aversive withdrawal symptoms, and 2) heart rate reactivity and subjective distress to an in-lab stressor. H1b: Aversive symptoms of UP food withdrawal will predict greater UP food intake and higher blood glucose levels when trying to adhere to a low UP diet. Aim 2: To investigate whether increased motivational salience of UP food cues emerges in response to reduced UP food intake, and whether this predicts failure to maintain a low-UP diet. H2a: Reducing UP food intake will result in increased motivational salience of UP food cues, as indicated by 1) EMA reports of UP food craving, 2) heart rate reactivity and subjective craving in a simulated fast-food restaurant, 3) heightened reinforcement value for UP food relative to other reinforcers, and 4) greater reward-related neural response to UP food cues. H2b: Increased motivational salience of UP food cues will predict greater UP food intake and higher blood glucose levels when trying to adhere to a low UP diet.

Sponsor: University of Michigan

Who Can Participate

Inclusion Criteria

22 to 60 years of age
English-speaking
Must own an Android or iPhone Smartphone
Live within a 1-hour radius of the laboratory
endorsement of \> 4 symptoms on the YFAS 2.0 completed during eligibility screener; at the time of consent, symptom count must remain above threshold for food addiction (this discrepany is based on a previously found tendency during pilot testing to overestimate food addiction symptoms at the time of screening)
Willing and able to follow specific dietary instructions provided by the study team
Willing and able to attend 3 in-person lab visits
Willing to complete 4 phone interviews about foods eaten in the past 24 hours
Willing to report daily intake of food
Like the taste of chocolate milkshake (for fMRI scan eligibility only).

Exclusion Criteria

participants with a self-reported BMI \< 18.5 and \> 40
Current diagnosis of disorder that may impact study results or the ability to safely complete study tasks (hypothyroidism (uncontrolled by medication), diabetes, etc.)
History of food allergies
Unable to respond to brief questionnaires within 90-minutes during the day
Work night shifts or irregular shifts
Restrictive dietary requirements (e.g., vegan) or high levels of picky eating
Medications (e.g., insulin, antipsychotic medications) that may impact study results or safe completion of study tasks
Diagnosis of severe mental illness (e.g., schizophrenia, bipolar disorder)
Diagnosis of a restrictive eating disorder (e.g., Anorexia Nervosa, Bulimia Nervosa, purging disorder) within the last 5 years
Current diagnoses of disorders that can impact reward/metabolic functioning
20+ pound weight fluctuation in the last 3-months
Prior weight loss surgery (e.g., bariatric surgery)
Currently pregnant, breastfeeding, trying to get pregnant, or within 6-months of having given birth
High levels or high-risk intake of alcohol or caffeine
Use of tobacco or nicotine in the past month
Use of THC cannabis within the past week
Unwillingness to abstain from THC cannabis, tobacco or nicotine during the main portion of the study (\~22 days)
fMRI contraindications (e.g., claustrophobia, metal implants).
inability to complete a random report within 90 minutes

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT06044285) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Food Addiction Treatment Options in Ann Arbor, MI

If you're searching for food addiction treatment options in Ann Arbor, MI, this clinical trial (NCT06044285) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this clinical trial. You'll receive care from experienced food addiction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all food addiction clinical trials near you to find additional studies recruiting in your area.

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