New Haven, CTNCT07281014Now EnrollingIRB Ready

Heart Failure Clinical Trial in New Haven, CT

Access cutting-edge heart failure treatment through this clinical trial at a research site in New Haven. Study-provided care at no cost to qualified participants.

Sponsored by Yale University

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Expert Care in New Haven

Access heart failure specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure treatment provided free

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Check if you qualify for this heart failure clinical trial in New Haven, CT

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Why Participate?

  • No-Cost Study Care

  • Local to New Haven

    Convenient for CT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit New Haven site if eligible
  4. 4Begin participation

About This Heart Failure Study in New Haven

The purpose of this research study is to understand the biology related to the potential shortcomings of existing anti-aldosterone therapy.

Sponsor: Yale University

Who Can Participate

Inclusion Criteria

Chronic stable heart failure at optimal volume status. Inclusion will require participants to be NYHA class I or II.
eGFR \> 30 ml/min/1.73m2
Serum potassium ≤5.0 meq/L and ≥3.5 meq/L
Stable heart failure medications without need or expectation for changes during the 8-week study period
Free from heart failure decompensation for the preceding 60 day
Systolic blood pressure \>90 mmHg if not taking an MRA at screening. If patients are already taking an MRA at the time of screening a systolic blood pressure needs to be \>80 mmHg.

Exclusion Criteria

Uncontrolled hypertension (SBP \> 160 mmHg)
Severe bladder dysfunction
Current MRA dose \> 50mg spironolactone or equivalent or non MRA potassium sparing diuretic such as amiloride
Contraindication to initiation or withdrawal of spironolactone per study procedures
History of severe hyperkalemia (K\>6.0 meq/l)
Brittle volume sensitive heart failure, recurrent flash pulmonary edema, restrictive cardiomyopathy or other pathology that would make aldosterone infusion high risk
Pregnant or breastfeeding
Women of childbearing potential that are not receiving a highly effective form of contraception. Females of childbearing potential must agree to use a highly effective method of birth control until 14 days after the last dose of study drug. The following are highly effective methods for this study:
Combined (estrogen and progestogen containing) hormonal contraception associated with inhibition of ovulation: oral, intravaginal, or transdermal
Progestogen-only hormonal contraception associated with inhibition of ovulation: oral, injectable, or implantable
Intrauterine device (IUD)
Intrauterine hormone-releasing system (IUS)
Bilateral tubal occlusion
Vasectomized partner
Sexual abstinence

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in New Haven?

Yes, this clinical trial (NCT07281014) has an active research site in New Haven, CT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure Treatment Options in New Haven, CT

If you're searching for heart failure treatment options in New Haven, CT, this clinical trial (NCT07281014) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our New Haven research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure clinical trials near you to find additional studies recruiting in your area.

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