Charlottesville, VANCT05609097Now EnrollingIRB Ready

Heart Failure With Reduced Ejection Fraction Clinical Trial in Charlottesville, VA

Access cutting-edge heart failure with reduced ejection fraction treatment through this clinical trial at a research site in Charlottesville. Study-provided care at no cost to qualified participants.

Sponsored by University of Virginia

Quick Self-Assessment

See if you qualify for this Charlottesville location

Preparing your pre-screening questions…

Expert Care in Charlottesville

Access heart failure with reduced ejection fraction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure with reduced ejection fraction treatment provided free

Apply for This Charlottesville Location

Check if you qualify for this heart failure with reduced ejection fraction clinical trial in Charlottesville, VA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charlottesville

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charlottesville site if eligible
  4. 4Begin participation

About This Heart Failure With Reduced Ejection Fraction Study in Charlottesville

This study is trying to find out whether performing a hybrid aerobic-resistance exercise training program (titled PRIME: Peripheral Remodeling via Intermittent Muscular Exercise) results in better health outcomes than the traditional exercise training program (called COMBO) that is used in individuals with heart failure with reduced ejection fraction (HFrEF). Participants will be randomized (like the flip of a coin) to either PRIME (investigational) or the traditional exercise program (standard of care).

Sponsor: University of Virginia

Who Can Participate

Inclusion Criteria

Subjects must be able to communicate meaningfully with the investigator and must be legally competent to provide written informed consent.
Subjects may be of either sex with age \> 65 years.
Subjects must be diagnosed with HFrEF as per established echocardiographic criteria (New York Heart Association Class II-III) with an ejection fraction \<45%.
Cardiologist approve after thorough chart review and physical examination
Hemoglobin of at least 10.0 g/dL

Exclusion Criteria

Progressive worsening of exercise tolerance or dyspnea at rest or on exertion over previous 3-5 days
Significant ischemia at low exercise intensities (\<2 METS or \~50 W)
Uncontrolled diabetes (HbA1c \>10%)
Acute systemic illness of fever
Recent embolism (in the 6 weeks)
Deep Vein Thrombophlebitis
Active pericarditis or myocarditis
Severe aortic stenosis (aortic valve area \<1.0 cm2)
Regurgitant valvular heart disease requiring surgery
Myocardial infarction within previous 3 weeks
New onset atrial fibrillation (in the last 4 weeks)
Resting Heart Rate \>120bpm

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charlottesville?

Yes, this clinical trial (NCT05609097) has an active research site in Charlottesville, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure With Reduced Ejection Fraction Treatment Options in Charlottesville, VA

If you're searching for heart failure with reduced ejection fraction treatment options in Charlottesville, VA, this clinical trial (NCT05609097) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charlottesville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure with reduced ejection fraction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure with reduced ejection fraction clinical trials near you to find additional studies recruiting in your area.

More Heart Failure Trials in Charlottesville, VA

See all heart failure clinical trials recruiting in Charlottesville — not just this study.

Browse Heart Failure Trials in Charlottesville

Ready to Join in Charlottesville?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Charlottesville, VA