Inverness, FLNCT07465653Now EnrollingIRB Ready

Heart Failure With Reduced Ejection Fraction Clinical Trial in Inverness, FL

Access cutting-edge heart failure with reduced ejection fraction treatment through this clinical trial at a research site in Inverness. Study-provided care at no cost to qualified participants.

Sponsored by Novartis Pharmaceuticals

Quick Self-Assessment

See if you qualify for this Inverness location

Preparing your pre-screening questions…

Expert Care in Inverness

Access heart failure with reduced ejection fraction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure with reduced ejection fraction treatment provided free

Apply for This Inverness Location

Check if you qualify for this heart failure with reduced ejection fraction clinical trial in Inverness, FL

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Inverness

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Inverness site if eligible
  4. 4Begin participation

About This Heart Failure With Reduced Ejection Fraction Study in Inverness

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of HJB647 at two different doses in participants with chronic stable heart failure with reduced or mildly reduced ejection fraction (HFrEF/HFmrEF).

Sponsor: Novartis Pharmaceuticals

Who Can Participate

Inclusion Criteria

Participants eligible for inclusion in this study must meet all of the following criteria:
Men and women aged 18 years or older
Stable NYHA functional class II-III
NT-proBNP ≥600 pg/ml if in sinus rhythm or ≥900 pg/ml if in atrial fibrillation at screening
On stable standard of care therapy with sacubitril/valsartan with a dose of at least 49/51 mg BID for at least 4 weeks before screening.

Exclusion Criteria

Participants will be deemed ineligible for inclusion if they meet any of the following exclusion criteria:
Acute decompensated heart failure within 3 months prior to screening
SBP \<105 mmHg at screening or baseline.
Acute coronary syndrome, stroke, transient ischemic attack, cardiac, carotid or other major cardiovascular surgery, PCI, or carotid angioplasty within the 6 months prior to screening
Hemodynamically significant mitral and/or aortic valve disease, or any prior valve replacement, except mitral regurgitation secondary to LV dilation at screening
eGFR \<30 ml/min/1.73m2 at screening, as measured by the CKD-EPI formula
BMI \>40 kg/m2
Strong CYP3A4 inhibitors or inducers, sGC activators (vericiguat), PDE5 inhibitors, and nitroglycerin products
Women of childbearing potential Further eligibility criteria might apply in alignment with the trial protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Inverness?

Yes, this clinical trial (NCT07465653) has an active research site in Inverness, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure With Reduced Ejection Fraction Treatment Options in Inverness, FL

If you're searching for heart failure with reduced ejection fraction treatment options in Inverness, FL, this clinical trial (NCT07465653) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Inverness research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure with reduced ejection fraction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure with reduced ejection fraction clinical trials near you to find additional studies recruiting in your area.

More Heart Failure Trials in Inverness, FL

See all heart failure clinical trials recruiting in Inverness — not just this study.

Browse Heart Failure Trials in Inverness →

Browse More Trials by Condition

Heart Failure TrialsRheumatoid Arthritis TrialsUlcerative Colitis TrialsErectile Dysfunction TrialsFanconi Anemia TrialsAll Conditions →

Ready to Join in Inverness?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Inverness, FL