Indianapolis, INNCT06568601Now EnrollingIRB Ready

Hypercholesterolemia Clinical Trial in Indianapolis, IN

Access cutting-edge hypercholesterolemia treatment through this clinical trial at a research site in Indianapolis. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

Quick Self-Assessment

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Expert Care in Indianapolis

Access hypercholesterolemia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hypercholesterolemia treatment provided free

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Check if you qualify for this hypercholesterolemia clinical trial in Indianapolis, IN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Indianapolis

    Convenient for IN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Indianapolis site if eligible
  4. 4Begin participation

About This Hypercholesterolemia Study in Indianapolis

Statins are the most cost-effective medications to lower cholesterol and cardiovascular disease (CVD) risk. However, many patients at high-risk for CVD do not accept or adhere to statins. This gap in patient's use of statins limits the full impact of these effective medications resulting in higher cholesterol levels and CVD risk. The main barriers to using statins are patients' perceived lack of benefit, excess risk of statin toxicity as well as their misperceptions of their CVD risk. Statin pharmacogenomic testing - an application of precision medicine - is a readily available, feasible, and inexpensive intervention that addresses this barrier by using genetic testing to identify the nearly 1 out of 2 patients with enhanced benefit and/or reduced risk of statin toxicity or increased risk for CVD. By communicating statin pharmacogenomic test results to Veterans at high-risk for CVD not taking statin therapy, the investigators aim to improve patients' perceptions of their risk of CVD and statins and, in turn, their acceptance of and adherence to statins to reduce their cholesterol levels and CVD risk.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Patients will be included in the analysis if they:
Are a Veteran
Aged 40-75 years
Diabetes mellitus or cardiovascular disease (coronary, cerebral, or peripheral artery disease)
An upcoming primary care appointment in the next 4 months
No active statin prescription (any time/dose, VA, or non-VA) in the prior 6 months
English speaking
At least 1 current active VA prescription
At least 1 primary care appointment within the prior 2 years

Exclusion Criteria

Non-Veterans
End-stage renal disease
History of rhabdomyolysis
Active treatment for non-dermatologic cancer
Known, prior SLCO1B1 genetic test results
Liver cirrhosis
Palliative care or hospice in 1-year prior to admission, during hospital stay, or at discharge
Active prescription for PCSK9 inhibitor
Inability to provide informed consent due to language impairment, cognitive disease, or other similar factors at the discretion of the research assistant or project coordinator.
Active enrollment in a different, interventional clinical trial, at the discretion of PI.
History of allogeneic stem cell transplant or liver transplant.
Documentation of specific adverse drug reactions thought to be attributed to statins:
Myopathy with associated elevation in creatinine kinase \> 10x upper limit of normal
Elevated AST/ALT
Others at discretion of PI

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Indianapolis?

Yes, this clinical trial (NCT06568601) has an active research site in Indianapolis, IN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hypercholesterolemia Treatment Options in Indianapolis, IN

If you're searching for hypercholesterolemia treatment options in Indianapolis, IN, this clinical trial (NCT06568601) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Indianapolis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hypercholesterolemia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hypercholesterolemia clinical trials near you to find additional studies recruiting in your area.

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