Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for High Cholesterol Clinical Trials
High Cholesterol clinical trials are recruiting across 58 cities. Here are the cities with the most active studies:
High Cholesterol Trial Phases
23 research organizations are sponsoring high cholesterol trials.
About High Cholesterol
High cholesterol occurs when there is too much cholesterol in the blood, increasing the risk of heart disease and stroke. It has no symptoms and is detected through blood tests. Management includes diet changes, exercise, and medications such as statins.
Clinical trials are advancing new treatments for high cholesterol. Currently, 28 studies are recruiting a combined 76,652 participants across the United States. Research is being conducted by 23 organizations including University of Massachusetts, Worcester, National Heart, Lung, and Blood Institute (NHLBI), University of Pennsylvania and 20 others.
2026 High Cholesterol Research Landscape
As of July 2026, the high cholesterol clinical trial landscape includes 28 actively recruiting studies across 58 cities in the United States. These studies are collectively seeking 76,652 participants, with an average enrollment target of 2,738 per study.
The research spans multiple phases of development: 12 studies are in NA, 6 studies are in PHASE3, 5 studies are in PHASE2, 1 study is in EARLY_PHASE1, 1 study is in PHASE1. The presence of Phase 3 trials indicates that some high cholesterol treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 23 different organizations, including University of Massachusetts, Worcester, National Heart, Lung, and Blood Institute (NHLBI), University of Pennsylvania, Arrowhead Pharmaceuticals, Regeneron Pharmaceuticals, and 18 others. The large number of sponsors reflects significant research interest and investment in high cholesterol treatment advancement.
Geographically, high cholesterol trials are most concentrated in Boca Raton, Florida (4 trials); New York, New York (4 trials); Cincinnati, Ohio (3 trials); Washington D.C., District of Columbia (3 trials); San Francisco, California (3 trials) and 7 other cities.
Featured High Cholesterol Studies
Highlighted recruiting studies for high cholesterol, selected by enrollment size and research scope.
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful decrease in chronic disease by monitoring conditions such as hypertension, diabetes, depression, hyperlipidemia, and asthma through clinical measures. The main question it ...
Causes and Natural History of Dyslipidemias
This study will evaluate people with dyslipidemias - disorders that affect the fat content in the blood. Fats, or lipids, such as cholesterol and triglycerides, are carried in the blood in particles called lipoproteins. These particles are involved in causing blood vessel diseases that can lead to conditions like atherosclerosis (hardening of the arteries) or heart attack. Participants will underg...
Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions
Background: The right amount of fats in the blood (cholesterol and triglycerides) are a key part of a healthy organism. Too much or too little of these fats may manifest as diseases (dyslipidemia). There are many causes for these abnormalities, but some are genetically determined and we would like to better understand the progression of these conditions over time. Objective: This natural histor...
Frequently Asked Questions About High Cholesterol Clinical Trials
Are there high cholesterol clinical trials near me?
Yes, there are 28 high cholesterol clinical trials currently recruiting across 58+ cities in the United States, including Boca Raton, Florida; New York, New York; Cincinnati, Ohio. Browse the studies above to find one at a location convenient for you.
How do I join a high cholesterol clinical trial?
To join a high cholesterol clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are high cholesterol clinical trials free?
Yes, participation in high cholesterol clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of high cholesterol treatments are being studied?
Current high cholesterol clinical trials are testing a range of approaches across NA (12 studies), PHASE3 (6 studies), PHASE2 (5 studies), EARLY_PHASE1 (1 study), PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 23 research organizations.
Is it safe to participate in high cholesterol clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov