San Antonio, TXNCT07053800Now EnrollingIRB Ready

Lupus Nephritis Clinical Trial in San Antonio, TX

Access cutting-edge lupus nephritis treatment through this phase 2 clinical trial at a research site in San Antonio. Study-provided care at no cost to qualified participants.

Sponsored by Autolus Limited

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Expert Care in San Antonio

Access lupus nephritis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related lupus nephritis treatment provided free

Apply for This San Antonio Location

Check if you qualify for this lupus nephritis clinical trial in San Antonio, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Antonio

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Antonio site if eligible
  4. 4Begin participation

About This Lupus Nephritis Study in San Antonio

The purpose of this trial is to evaluate the efficacy and safety of obecabtagene autoleucel (obe-cel) administered once following lymphodepletion in participants with severe, refractory systemic lupus erythematosus (SLE) and active lupus nephritis (LN).

Sponsor: Autolus Limited

Who Can Participate

Inclusion Criteria

Willing and able to give written informed consent for participation in the study or written informed consent signed by a legal guardian or representative
Ability and willingness to adhere to protocol's Schedule of Activities and other requirements
Participants must be 12 to 65 years of age inclusive at the time of signing the informed consent.
Female Participants: - a female participant is eligible to participate if she is not pregnant or breastfeeding
Diagnosis of SLE fulfilling the 2019 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) Classification Criteria for Systemic Lupus Erythematosus.
Positive for at least 1 of the following autoantibodies: antinuclear antibodies (ANA), or anti-dsDNA or anti-Smith.
Severe, Active SLE defined as:
SLEDAI-2K score of ≥ 8 points AND
Severe active LN based on a renal biopsy: Class III, IV or V (V only in combination with class III or IV)
Refractory SLE defined as failure to previous lines of therapy

Exclusion Criteria

Prior treatment at any time with anti-CD19 therapy
More than 1 acute, severe lupus-related flare during screening that needs immediate treatment and/or makes the immunosuppressive washout impossible
Significant, likely irreversible organ damage related to SLE (e.g., end-stage renal disease) that in the opinion of the Investigator renders CD19 CAR T cell therapy unlikely to benefit the participant
History of primary antiphospholipid antibody syndrome
Active or uncontrolled fungal, bacterial, or viral infection
History of malignant neoplasms unless disease free for at least 24 months
History of heart, lung, renal, liver transplant or hematopoietic stem cell transplant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Antonio?

Yes, this clinical trial (NCT07053800) has an active research site in San Antonio, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Lupus Nephritis Treatment Options in San Antonio, TX

If you're searching for lupus nephritis treatment options in San Antonio, TX, this clinical trial (NCT07053800) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Antonio research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced lupus nephritis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all lupus nephritis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · San Antonio, TX