Charleston, SCNCT07226011Now EnrollingIRB Ready

Major Depression Clinical Trial in Charleston, SC

Access cutting-edge major depression treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by Medical University of South Carolina

Quick Self-Assessment

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Expert Care in Charleston

Access major depression specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depression treatment provided free

Apply for This Charleston Location

Check if you qualify for this major depression clinical trial in Charleston, SC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Major Depression Study in Charleston

In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulation through electrodes placed on their scalp. The study begins with a safety run-in, where the first few participants will receive stimulation at gradually increasing levels (2, 4, and 6 milliamps) while being closely monitored. If no serious side effects are found, later participants will receive repeated 6 milliamp sessions for 5 days total. Investigators will check skin comfort, mood, and overall tolerability after each session.

Sponsor: Medical University of South Carolina

Who Can Participate

Inclusion Criteria

Ages 18-70.
Current MDD diagnosis (MINI v7).
Baseline PHQ-9 \> 9.
Capacity to consent
Fluent English.

Exclusion Criteria

Bipolar or psychotic disorder
Primary anxiety disorders without concomitant major depression as defined above
Current significant suicidal ideation or behaviors require a higher level of care.
Use of neuromodulation therapies (e.g., ECT, TMS, VNS) within the past 6 months.
History of seizures, implanted cranial/ cardiac metal, or neurosurgery.
Use of medications that significantly reduce seizure threshold
Frequent/severe HA
Personal history of head trauma, concussion, or TBI
Catatonic or otherwise unable to perform the consent process
Current alcohol or substance-use disorder (moderate-severe).
Any non-uniformities in the skin under the electrode site, including eczema, severe rashes, hyperhidrosis, communicable skin disorders, sensitive skin (ex. eczema, severe rashes), blisters, open wounds, burns including sunburns, cuts or irritation (e.g. due to shaving), or other skin defects or lesions, as determined by clinical personnel
Pregnancy (urine test required for women of childbearing potential).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT07226011) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depression Treatment Options in Charleston, SC

If you're searching for major depression treatment options in Charleston, SC, this clinical trial (NCT07226011) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced major depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depression clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC