Birmingham, ALNCT07226661Now EnrollingIRB Ready

Major Depressive Disorder (MDD) Clinical Trial in Birmingham, AL

Access cutting-edge major depressive disorder (mdd) treatment through this phase 2 clinical trial at a research site in Birmingham. Study-provided care at no cost to qualified participants.

Sponsored by Supernus Pharmaceuticals, Inc.

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Expert Care in Birmingham

Access major depressive disorder (mdd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder (mdd) treatment provided free

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Check if you qualify for this major depressive disorder (mdd) clinical trial in Birmingham, AL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Birmingham

    Convenient for AL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Birmingham site if eligible
  4. 4Begin participation

About This Major Depressive Disorder (MDD) Study in Birmingham

This study will evaluate the efficacy and safety of SPN-821 in adults with major depressive disorder

Sponsor: Supernus Pharmaceuticals, Inc.

Who Can Participate

Inclusion Criteria

Current diagnosis of MDD according to the DSM-5 for either single or recurrent MDE without psychotic features confirmed by the MINI
Duration of current MDE of at least 8 weeks
MADRS total score of ≥ 24 at the Screening Visit and Day 1 Visit
CGI-S score of ≥ 4 (moderately ill or worse) at the Screening Visit and Day 1 Visit
Stable, therapeutic dose of one of the following protocol-approved ADTs as a monotherapy for ≥ 8 weeks before the Screening Visit and ≥ 10 weeks at the Day 1 Visit. Additionally, inadequate response to the current ADT (less than 50% improvement in depressive symptoms) as confirmed by the ATRQ Investigator administered.

Exclusion Criteria

MADRS total score change of ≥ 25% from the Screening Visit to Day 1 Visit
History of treatment resistant depression (TRD) defined as 3 or more failed ADTs of adequate dose (per ATRQ) and duration (at least 8 weeks) for the current MDE
History of alcohol or substance use disorder according to DSM-5 criteria 6 months before the Screening Visit
Evidence of significant risk for suicidal behavior during participation in the study in the Investigator's opinion
Lifetime diagnosis of any psychotic disorder including MDD with psychosis, MDD with mixed features, bipolar I/II disorder, bipolar depression, schizophrenia, posttraumatic stress disorder, autism spectrum disorder, or any personality disorder or intellectual disability that would affect the ability of the participant to enroll in the study
Diagnosis less then 12 months before screening of severe obsessive-compulsive disorder, acute stress disorder, panic disorder, eating disorders, or any other psychiatric condition that has been the primary focus of treatment, or diagnosis of generalized anxiety disorder less then 6 months before screening.
History of cardiovascular, respiratory, gastrointestinal, renal, hepatic, and hematologic disorders, or other medical disorders that could impose undue risk or compromise the study in the Investigator's opinion
Clinically significant abnormal result prior to Day 1 Visit per Investigator's judgment or abnormal renal function.
Requires treatment with a medication or other substance that is prohibited by the protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Birmingham?

Yes, this clinical trial (NCT07226661) has an active research site in Birmingham, AL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder (MDD) Treatment Options in Birmingham, AL

If you're searching for major depressive disorder (mdd) treatment options in Birmingham, AL, this clinical trial (NCT07226661) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Birmingham research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced major depressive disorder (mdd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder (mdd) clinical trials near you to find additional studies recruiting in your area.

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