Salt Lake City, UTNCT05895747Now EnrollingIRB Ready

Major Depressive Disorder Clinical Trial in Salt Lake City, UT

Access cutting-edge major depressive disorder treatment through this phase 2 clinical trial at a research site in Salt Lake City. Study-provided care at no cost to qualified participants.

Sponsored by University of Utah

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Expert Care in Salt Lake City

Access major depressive disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder treatment provided free

Apply for This Salt Lake City Location

Check if you qualify for this major depressive disorder clinical trial in Salt Lake City, UT

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Salt Lake City

    Convenient for UT residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Salt Lake City site if eligible
  4. 4Begin participation

About This Major Depressive Disorder Study in Salt Lake City

This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression. Subjects will be randomized between 5-HTP 100mg BID + creatine 5g daily, 5-HTP 200mg BID + creatine 10g daily, vs double placebo, for 8 weeks. The ability of the interventions to affect biomarkers associated with depression will be assessed using brain phosphorus magnetic resonance spectroscopy, functional connectivity imaging, and plasma serotonin levels.

Sponsor: University of Utah

Who Can Participate

Inclusion Criteria

Adults age 18-65 years inclusive
Current diagnosis of MDD identified by the MINI (Mini Neuropsychiatric Interview)
Current HAM-D17 score of \>= 16
Adequate adherence to any FDA approved SSRI or SNRI for at least 8 weeks
Right-handed
Residing at \> 4000 ft for at least 12 weeks

Exclusion Criteria

Any non-MDD and non-anxiety psychiatric diagnosis, as identified by the MINI
History of or current diagnosis of renal disease, such as chronic renal failure, acute renal failure or end stage renal disease
Current colitis or diverticulitis
History of or current pulmonary disease (except well controlled asthma)
Current smoking
History of cardiac disease or QTc \> 500ms
History of fibromyalgia or any rheumatological condition
History of or current seizure disorder
Current serious suicide risk identified by the Columbia Severity Suicide Rating Scale
Current treatment with an antipsychotic, mood stabilizer, or non-SSRI/SNRI antidepressant except for bupropion at FDA-approved doses or trazodone up to 200mg, or use of any supplements apart from standard multivitamins
Positive pregnancy test, pregnancy, failure to use adequate birth control method
Previous diagnosis of serotonin syndrome or evidence of serotonin syndrome
Pre-existing eosinophilia (absolute eosinophil count \> 500/uL)
Contraindications to MRI: ferromagnetic implants, implanted devices, claustrophobia

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Salt Lake City?

Yes, this clinical trial (NCT05895747) has an active research site in Salt Lake City, UT that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder Treatment Options in Salt Lake City, UT

If you're searching for major depressive disorder treatment options in Salt Lake City, UT, this clinical trial (NCT05895747) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Salt Lake City research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced major depressive disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Salt Lake City, UT