Boston, MANCT07548476Now EnrollingIRB Ready

Metastatic Bladder Cancer Clinical Trial in Boston, MA

Access cutting-edge metastatic bladder cancer treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Dana-Farber Cancer Institute

Quick Self-Assessment

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Expert Care in Boston

Access metastatic bladder cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related metastatic bladder cancer treatment provided free

Apply for This Boston Location

Check if you qualify for this metastatic bladder cancer clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Metastatic Bladder Cancer Study in Boston

The goal of this study is to evaluate the feasibility and preliminary efficacy of a combined acupuncture and exercise intervention for the management of chemotherapy-induced peripheral neuropathy (CIPN) in participants with bladder cancer receiving enfortumab vedotin (EV) and pembrolizumab (Pembro). The names of the two study groups in this research study are: * Acupuncture + Virtual Exercise (AVE) * Virtual Exercise Only (VE)

Sponsor: Dana-Farber Cancer Institute

Who Can Participate

Inclusion Criteria

Age ≥ 18 years old
Diagnosed with pathologically proven urothelial cancer (UC)
Have received at least one cycle of EV-Pembro treatment with enrollment occurring after the 1st cycle and prior to the 4th cycle
Self-reported ability to walk for 6 minutes and/or 2 blocks
Deemed acceptable for exercise by their treating provider
Sedentary, currently engaging in less than or equal to 60 minutes of moderate or vigorous structured exercise/week, as assessed by the Godin Leisure-Time Exercise Questionnaire
Willing to adhere to all study-related procedures, including randomization to either treatment group
Referrals to physical therapy are allowed during the study if necessary
Participants taking any of medications listed below must be on a stable regimen, with no changes in the past three months. Use of these medications may continue while on study.
Duloxetine, amitriptyline, nortriptyline, gabapentin, and pregabalin
Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety of efficacy assessment of investigational regimen will be eligible.

Exclusion Criteria

History of documented grade 2 or greater peripheral or motor neuropathy prior to EV-Pembro initiation; may confound assessment of the intervention's preventative effect
Patients with uncontrolled medical conditions that would preclude them from participating in moderate-to-vigorous intensity exercise in a virtual setting. Given the exercise environment is virtual, only patients with stable medical conditions should be enrolled to ensure their safety. Physical Activity Readiness Questionnaire (PARQ+) will be used during screening to facilitate conversations about present or historical medical conditions
Having continued grade 2 or higher adverse effects of their current treatment (EV-Pembro)
Receiving more than 10mg prednisone daily for any condition
History of bleeding diathesis (von Willebrand disease, hemophilia A/B)
Known history of seizure disorder or taking antiepileptic drugs
Participate in more than 60 minutes of moderate or vigorous structured exercise/week Investigators will not include the following special populations:
Adults unable to consent
Individuals who are not yet adults (infants, children, teenagers \< 18 years)
Pregnant women

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07548476) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Metastatic Bladder Cancer Treatment Options in Boston, MA

If you're searching for metastatic bladder cancer treatment options in Boston, MA, this clinical trial (NCT07548476) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced metastatic bladder cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all metastatic bladder cancer clinical trials near you to find additional studies recruiting in your area.

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