Detroit, MINCT02703207Now EnrollingIRB Ready

Obstructive Sleep Apnea Clinical Trial in Detroit, MI

Access cutting-edge obstructive sleep apnea treatment through this clinical trial at a research site in Detroit. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Detroit

Access obstructive sleep apnea specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obstructive sleep apnea treatment provided free

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Check if you qualify for this obstructive sleep apnea clinical trial in Detroit, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Detroit

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Detroit site if eligible
  4. 4Begin participation

About This Obstructive Sleep Apnea Study in Detroit

Cognitive dysfunction in the aging Veteran population is a growing health concern in the Veterans Health System. It is not known whether OSA coexisting with COPD will enhance the risk for cognitive dysfunction. The investigators sought to investigate whether these two highly prevalent diseases, that often co-exist as the 'Overlap Syndrome', combine to enhance cognitive impairment in the elderly Veteran population. Thus, the investigators will study whether elderly patients with Overlap syndrome have increased cognitive deficits compared with OSA or COPD alone. Additionally, treatment of OSA with positive airway pressure (PAP) has been shown to improve neurocognitive function in moderate-to-severe OSA while cognitive decline in COPD may be reversible through treatment with long-term oxygen therapy. The investigators will also study whether treatment with positive airway pressure (PAP) and supplemental oxygen vs PAP alone will improve cognitive function and improve quality of life of elderly Veterans.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

OSA defined by the International classification of Sleep Disorders-322 diagnostic criteria with moderate-to-severe disease, i.e. apnea hypopnea index (AHI) 15\
per hour by polysomnography
Moderate-to-severe COPD defined by GOLD 2 and 3 (Global Obstructive Lung Disease) 23 criteria with FEV1/FVC ratio \<70% and FEV1 \>30% and \<80% of predicted based on PFT done within the past 1 year and a past significant history (10 pack-years) of smoking
Age 60 years
Male or female gender

Exclusion Criteria

Overlap Syndrome with mild OSA plus mild COPD
Central sleep apnea defined as central apnea index \>5 per hour
Already on daytime oxygen or nighttime CPAP, NIPPV, oral appliance
Current smokers
Pregnant women
Disorders of hypoventilation due to known neuromuscular or chest wall diseases\*\
Patients with significant restrictive lung disease on pulmonary function testing
Recent admission for any acute illness within the prior 4 months
Current psychiatric illness requiring sedating medications
Use of hypnotics, anxiolytics, sedating antidepressants, anticonvulsants, sedating antihistamines, stimulants, or other medications likely to affect alertness or daytime functioning for Aim 3/4
For Aim 3 and 4 only, existing depression as assessed by the PHQ (Patient Health Questionnaire)-9 (score \>10)
History of learning disability
Inability to sign consent
Epworth sleepiness score 18 or a near-miss or prior automobile accident due to sleepiness within the past 12 months
Patients with unstable heart disease, decompensated heart failure, ejection fraction\<45% or uncontrolled arrhythmias
Patients unable to use either a nasal or face mask (e.g., facial trauma)
Consumption of \> 2 alcoholic beverages per day or past history of excessive alcohol use
Current use of illicit drugs
Patients who have problems with vision or dexterity and hence, cannot use CPAP/NIPPV
Life expectancy is less than 6 months

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Detroit?

Yes, this clinical trial (NCT02703207) has an active research site in Detroit, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obstructive Sleep Apnea Treatment Options in Detroit, MI

If you're searching for obstructive sleep apnea treatment options in Detroit, MI, this clinical trial (NCT02703207) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Detroit research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obstructive sleep apnea specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obstructive sleep apnea clinical trials near you to find additional studies recruiting in your area.

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