Springfield, ILNCT06883123Now EnrollingIRB Ready

Open Angle Glaucoma Clinical Trial in Springfield, IL

Access cutting-edge open angle glaucoma treatment through this clinical trial at a research site in Springfield. Study-provided care at no cost to qualified participants.

Sponsored by Prairie Eye Center

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Expert Care in Springfield

Access open angle glaucoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related open angle glaucoma treatment provided free

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Check if you qualify for this open angle glaucoma clinical trial in Springfield, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Springfield

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Springfield site if eligible
  4. 4Begin participation

About This Open Angle Glaucoma Study in Springfield

A randomized, multi-site, parallel-group, prospective study of patients who are adults with a diagnosis of mild to moderate open-angle glaucoma (OAG), currently on an on-label use of combination topical medication of Cosopt and Latanoprost for a minimum of 1 month.

Sponsor: Prairie Eye Center

Who Can Participate

Inclusion Criteria

Adults aged Eighteen (18) years and older with a diagnosis of mild to moderate open-angle glaucoma (OAG), currently on an on-label use of combination topical medication of Cosopt and Latanoprost for a minimum of 1 month. Evidence of optic nerve damage will be based on AAO Preferred Practice Patterns guidelines using either or both of the following:
Optic disc or retinal nerve fiber layer (RNFL) structural abnormalities
Diffuse or focal narrowing, or notching, of the optic disc rim, especially at the inferior or superior poles, which forms the basis for the ISNT rule
Progressive narrowing of the neuroretinal rim with an associated increase in cupping of the optic disc
Diffuse or localized abnormalities of the parapapillary RNFL, especially at the inferior or superior poles
Disc rim, parapapillary RNFL, or lamina cribrosa hemorrhages
Optic disc neural rim asymmetry of the two eyes consistent with loss of neural tissue
Large extent of parapapillary atrophy
Reliable and reproducible visual field abnormality considered a valid representation of the subject's functional status
Visual field damage consistent with RNFL damage (e.g. nasal step, arcuate field defect, or paracentral depression in clusters of test sites)
Visual field loss across the horizontal midline in one hemifield that exceeds loss in the opposite hemifield (in early/ moderate cases)
Absence of other known explanations (e.g. optic disc drusen, optic nerve pit)
Mean diurnal IOP ≥ 18 mmHg and \< 28 mmHg at baseline in at least one eye with an inter-eye IOP difference \< 5 mmHg.
A central corneal thickness (CCT) within the range of 450-650 µm

Exclusion Criteria

Patients with prior ocular procedures or intraocular surgery within 1 year prior to baseline (e.g. cataract surgery).
Patients with prior history of glaucoma surgeries or laser treatment except patients with history of SLT \>1 yr prior to baseline.
Contraindications or known hypersensitivity to any or all the study medications including Rocklatan, Simbrinza, Cosopt and Latanoprost or related class of drugs.
Patients with known history or presence of uncontrolled systemic diseases including diseases that, in investigator's opinion, may make it unsafe or undesirable for the subject to participate in the study and/ or limit adherence.
Patients with known history or presence of significant ocular diseases including corneal diseases, dystrophies or abnormalities that would prevent accurate IOP readings with GAT.
Patients with a history of uncontrolled IOP with the combination of either Rocklatan + Simbrinza or Cosopt + Latanoprost dual therapy.
Significant ocular surface findings (e.g. hyperemia, irritation) found during slit lamp examination that might affect the study.
Chronic use of any systemic medication for chronic diseases that may affect IOP.
Subjects who are pregnant, lactating or planning a pregnancy.
Any condition in the opinion in the investigator that would potentially confound the results of this study

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Springfield?

Yes, this clinical trial (NCT06883123) has an active research site in Springfield, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Open Angle Glaucoma Treatment Options in Springfield, IL

If you're searching for open angle glaucoma treatment options in Springfield, IL, this clinical trial (NCT06883123) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Springfield research site is actively enrolling participants for this clinical trial. You'll receive care from experienced open angle glaucoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all open angle glaucoma clinical trials near you to find additional studies recruiting in your area.

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