Boston, MANCT07473713Now EnrollingIRB Ready

Osteopenia Clinical Trial in Boston, MA

Access cutting-edge osteopenia treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Tufts Medical Center

Quick Self-Assessment

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Expert Care in Boston

Access osteopenia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related osteopenia treatment provided free

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Check if you qualify for this osteopenia clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Osteopenia Study in Boston

The goal of this clinical trial is to learn if veverimer will reduce urinary net acid excretion leading to reduced bone resorption in healthy adults with osteopenia. The main questions it aims to answer are: * How much does each dose of veverimer (vs. placebo) reduce 24-hr urinary net acid excretion. * Describe the safety of veverimer based on changes in serum bicarbonate and potassium. * Assess the changes in bone resorption. * Assess the changes in bone formation. * Explore the effect of veverimer on physical performance. Participants will: * Take veverimer or placebo every day or every other day for 8 weeks * Visit the clinic a total of 8 times (including screening) for checkups and testing * Keep a medication diary tracking each day they take the study drug

Sponsor: Tufts Medical Center

Who Can Participate

Inclusion Criteria

Community dwelling adults age 50 years and older (approximately equal numbers of men and women).
Men should be sterile or agree to use contraception throughout the study.
Women must be postmenopausal, defined as no menses in the last 5 years (to reduce variability in change in bone resorption since menopause prompts a rapid increase in bone resorption).
Osteopenia will be defined as a bone mineral density (BMD) T-score at the lumbar spine, femoral neck, or total hip lower than -1 or higher than -2.5.
On a prescreening interview, candidates must report a usual diet associated with an acid load by our validated short questionnaire.
Estimated glomerular filtration rate (eGFR) must be 45 ml/min or greater.
Participants must agree not to change their exercise pattern or medication use during the study.
Participants must agree not to change their pattern of supplement use and not to use antacids during the study because most calcium supplements and other antacids add alkali.
Participants must agree to not change their eating habits or intentionally change their weight.

Exclusion Criteria

Normal BMD T-scores at all spine and hip sites, osteoporosis based on BMD T-score of -2.5 or less
Respiratory illness in last month
Chronic obstructive pulmonary disease (COPD)
Nausea/vomiting in last month
Malabsorption
Inflammatory bowel disease
Chronic diarrhea (defined as loose bowel movements daily) or constipation (≤ 2 stools per week)
Insulin-requiring diabetes or fasting plasma glucose \>125 mg/dl
Untreated thyroid disease
Current unstable heart disease
Malignancy (except non-melanoma skin cancer) or cancer therapy in last year
Alcohol use \>2 drinks/day.
Individuals who are unable to provide informed consent due to cognitive impairment.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07473713) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Osteopenia Treatment Options in Boston, MA

If you're searching for osteopenia treatment options in Boston, MA, this clinical trial (NCT07473713) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced osteopenia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all osteopenia clinical trials near you to find additional studies recruiting in your area.

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