Thousand Oaks, CANCT05988411Now EnrollingIRB Ready

Paroxysmal Atrial Fibrillation Clinical Trial in Thousand Oaks, CA

Access cutting-edge paroxysmal atrial fibrillation treatment through this clinical trial at a research site in Thousand Oaks. Study-provided care at no cost to qualified participants.

Sponsored by Vivek Reddy

Quick Self-Assessment

See if you qualify for this Thousand Oaks location

Preparing your pre-screening questions…

Expert Care in Thousand Oaks

Access paroxysmal atrial fibrillation specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related paroxysmal atrial fibrillation treatment provided free

Apply for This Thousand Oaks Location

Check if you qualify for this paroxysmal atrial fibrillation clinical trial in Thousand Oaks, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Thousand Oaks

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Thousand Oaks site if eligible
  4. 4Begin participation

About This Paroxysmal Atrial Fibrillation Study in Thousand Oaks

This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension scheduled for a redo AF ablation procedure for paroxysmal or persistent AF. Patients will be randomized to either i) AF ablation (Control) or ii) AF ablation + renal sympathetic denervation (Intervention).

Sponsor: Vivek Reddy

Who Can Participate

Inclusion Criteria

Planned for a redo AF ablation procedure (paroxysmal or persistent); (prior to randomization, a technically successful AF ablation procedure, defined as successful pulmonary vein isolation, if needed, as well as bidirectional block of any attempted anatomic lesion sets such as cavotricuspid isthmus line, roofline, mitral line and superior vena cava isolation, must have been completed). Note: the clinical recurrences must primarily be atrial fibrillation, and not atrial flutter/tachycardia (that is, a prospective patient may have a AFL/AT recurrences, but AF must be the dominant recurrent rhythm.)
History of hypertension and either:
Documented history of SBP≥160 or DBP≥100, or;
Receiving ≥1 antihypertensive medication;
Willingness to adhere to study restrictions and comply with all post-procedural follow-up requirements

Exclusion Criteria

Long-standing persistent AF (\>12 months); \>3 prior atrial fibrillation ablations (lifetime); AF ablation within 3 months of enrollment; extensive scar in left atrium.
Individual with valvular AF or AF due to a reversible cause
Prior treatment with other devices for hypertension including but not limited to ROX Coupler, Mobius stent, and/or the CVRx barostimulator device.
NYHA class IV congestive heart failure;
Individual has renal artery anatomy that is ineligible for treatment (as determined by renal angiography);
Main renal artery diameter \<3mm or \>8.0 mm
Main renal treatable artery length \< 20 mm (length may include proximal branches)
Presence of renal artery stenosis of any origin ≥30%
Calcification in renal arteries
Prior renal denervation procedure
Presence of abnormal kidney tumors
Renal artery aneurysm
Pre-existing renal stent or history of renal artery angioplasty
Pre-existing aortic stent or history of aortic aneurysm
Fibromuscular disease of the renal arteries
Iliac/femoral artery stenosis precluding insertion of the Paradise Catheter
Individual has an estimated glomerular filtration rate (eGFR) of less than 40mL/min/1.73m2, using the MDRD calculation;
Inability to undergo AF catheter ablation (e.g., presence of a left atrial thrombus, contraindication to all anticoagulation)
Individual with known allergy to contrast medium not amendable to treatment.
Life expectancy \<1 year for any medical condition
Individual has experienced a myocardial infarction, unstable angina, cerebrovascular accident, or heart failure admission within 3 months of the baseline visit.
Documented history of chronic active inflammatory bowel disorders such as Crohn's disease or ulcerative colitis.
Female participants who are pregnant or nursing.
Individual has known secondary hypertension.
Individual has a single functioning kidney (either congenitally or iatrogenically).
Individual has a known, unresolved history of drug use or alcohol dependency, lacks the ability to comprehend or follow instructions, or would be unlikely or unable to comply with study follow-up requirements.
Patients concurrently enrolled in any other investigational drug or device trial that would interfere with the conduction of this protocol.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Thousand Oaks?

Yes, this clinical trial (NCT05988411) has an active research site in Thousand Oaks, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Paroxysmal Atrial Fibrillation Treatment Options in Thousand Oaks, CA

If you're searching for paroxysmal atrial fibrillation treatment options in Thousand Oaks, CA, this clinical trial (NCT05988411) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Thousand Oaks research site is actively enrolling participants for this clinical trial. You'll receive care from experienced paroxysmal atrial fibrillation specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all paroxysmal atrial fibrillation clinical trials near you to find additional studies recruiting in your area.

More Atrial Fibrillation Trials in Thousand Oaks, CA

See all atrial fibrillation clinical trials recruiting in Thousand Oaks — not just this study.

Browse Atrial Fibrillation Trials in Thousand Oaks →

Browse More Trials by Condition

Atrial Fibrillation TrialsSpinal Muscular Atrophy TrialsAll Conditions →

Ready to Join in Thousand Oaks?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Thousand Oaks, CA