Brooklyn, NYNCT06752759Now EnrollingIRB Ready

Severe Depression Clinical Trial in Brooklyn, NY

Access cutting-edge severe depression treatment through this clinical trial at a research site in Brooklyn. Study-provided care at no cost to qualified participants.

Sponsored by Theresa Jacob, PhD, MPH

Quick Self-Assessment

See if you qualify for this Brooklyn location

Preparing your pre-screening questions…

Expert Care in Brooklyn

Access severe depression specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related severe depression treatment provided free

Apply for This Brooklyn Location

Check if you qualify for this severe depression clinical trial in Brooklyn, NY

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Brooklyn

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Brooklyn site if eligible
  4. 4Begin participation

About This Severe Depression Study in Brooklyn

This is a double-blind active placebo controlled clinical trial for individuals with moderate to severe depression. The purpose of this study is to assess if nebulized ketamine can reduce depressive symptoms.

Sponsor: Theresa Jacob, PhD, MPH

Who Can Participate

Inclusion Criteria

All individuals 18 years and older with a Montgomery-Asberg Depression Rating Scale score (MADRS) ≥ 20
Must have a diagnosis of moderate to severe Major Depressive Disorder (MDD)
Structured Clinical Interview for DSM-5 (SCID-5) will be performed to confirm MDD diagnosis

Exclusion Criteria

Adult patients with an allergy to Ketamine
Adult patients with an allergy to Midazolam
Individuals with a history of mania/hypomania or diagnosis of bipolar disorder
Patients on lithium and/or lamotrigine therapy
Recent or current homicidal ideation with an intent to act
MDD with psychotic features or current or past diagnosis of a psychotic disorder
No substance use disorder in the preceding 3 months except nicotine or caffeine or a positive urine screen for substances (except cannabis)
Diagnosis of obsessive-compulsive disorder, antisocial personality disorder, borderline personality disorder, posttraumatic stress disorder, intellectual disability, altered mental status, pregnant or breastfeeding patients,
Patients on \> 2 medications for hypertension
Patients with uncontrolled hypertension (BP \>140 mm Hg systolic and/or \>90 mm Hg diastolic on two separate readings at the time of screening)
Body weight of \> 150kg
Patients with history of congestive cardiac failure
Day of presentation, patients with unstable vital signs (systolic blood pressure \<90 or\>160 mm Hg, pulse rate \<50 or \>150 beats/min, and respiration rate \<10 or \>30 breaths/min)
Consumption of opioids within 24 hours of drug administration
Acutely intoxicated patients will also be excluded

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Brooklyn?

Yes, this clinical trial (NCT06752759) has an active research site in Brooklyn, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Severe Depression Treatment Options in Brooklyn, NY

If you're searching for severe depression treatment options in Brooklyn, NY, this clinical trial (NCT06752759) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Brooklyn research site is actively enrolling participants for this clinical trial. You'll receive care from experienced severe depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all severe depression clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Brooklyn, NY