Vallhala, NYNCT05987124Now EnrollingIRB Ready

Sinusoidal Obstruction Syndrome Clinical Trial in Vallhala, NY

Access cutting-edge sinusoidal obstruction syndrome treatment through this phase 2 clinical trial at a research site in Vallhala. Study-provided care at no cost to qualified participants.

Sponsored by New York Medical College

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Expert Care in Vallhala

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sinusoidal obstruction syndrome treatment provided free

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Check if you qualify for this sinusoidal obstruction syndrome clinical trial in Vallhala, NY

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Why Participate?

  • No-Cost Study Care

  • Local to Vallhala

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Vallhala site if eligible
  4. 4Begin participation

About This Sinusoidal Obstruction Syndrome Study in Vallhala

This research study is being done to determine the safety and tolerability of increasing doses of defibrotide within a single patient with sinusoidal obstructive syndrome (SOS)/veno-occlusive disease (VOD) after hematopoietic cell transplantation (HCT) associated with either kidney and/or lung impairment that has not obtained a complete response (CR) or progressed in severity with standard doses of defibrotide.

Sponsor: New York Medical College

Who Can Participate

Inclusion Criteria

HCT recipients (Auto or Allograft)
SOS/VOD as defined by Cairo/Cooke Diagnostic criteria (1) (Table 3) with either renal and/or pulmonary dysfunction as defined by Cairo/Cooke Grading criteria (1) (Appendix I).
Unresponsive to standard defibrotide therapy as defined by at least one of the following:
Patients with SOS/VOD failing to obtain a complete response (CR) defined by Grade I or less by Cairo/Cooke Grading criteria (1) (Appendix I). This would therefore include patients with stable disease after at least 14 days of defibrotide or partial response after at least 21 days of defibrotide (25mg/kg/day).
Progressive disease defined by progression of at least one grade or more from diagnostic grade as defined by Cairo/Cooke Grading criteria (1) (Appendix I) following at least 7 days of defibrotide (25mg/kg/day).
Age 1 month - 75 years

Exclusion Criteria

Patients who did not receive HCT.
Concomitant systemic anticoagulation (excluding central venous line management, fibrinolytic instillation for central venous line occlusion, management of intermittent dialysis or ultrafiltration of CVVH).
Active bleeding and/or hemorrhage of at least grade 2 and above.
History of development of Grade III/IV anaphylaxis probably or directly secondary to defibrotide.
Female patients who are pregnant or breast feeding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Vallhala?

Yes, this clinical trial (NCT05987124) has an active research site in Vallhala, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sinusoidal Obstruction Syndrome Treatment Options in Vallhala, NY

If you're searching for sinusoidal obstruction syndrome treatment options in Vallhala, NY, this clinical trial (NCT05987124) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Vallhala research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced sinusoidal obstruction syndrome specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sinusoidal obstruction syndrome clinical trials near you to find additional studies recruiting in your area.

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