Boston, MANCT05103566Now EnrollingIRB Ready

Subarachnoid Hemorrhage, Aneurysmal Clinical Trial in Boston, MA

Access cutting-edge subarachnoid hemorrhage, aneurysmal treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

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Expert Care in Boston

Access subarachnoid hemorrhage, aneurysmal specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related subarachnoid hemorrhage, aneurysmal treatment provided free

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Check if you qualify for this subarachnoid hemorrhage, aneurysmal clinical trial in Boston, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Subarachnoid Hemorrhage, Aneurysmal Study in Boston

This is a single-site, single-arm, open-label pilot study assessing the safety, feasibility, and efficacy of non-invasive vagus nerve stimulation (nVNS), gammaCore, for the acute treatment of aneurysmal subarachnoid hemorrhage (SAH) subjects in a neurocritical care setting. 25 patients will be enrolled, all treated with an active device. The primary efficacy outcomes are reduced aneurysm rupture rate, reduced seizure and seizure-spectrum activity, minimized hemorrhage grades, and increased survival.

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Male or female, 18-85 years of age
Ruptured aneurysmal SAH confirmed by angiography and repaired by neurosurgical clipping or endovascular occlusion (coiling)
Modified Glasgow Coma Scale (mGCS) score ≥ 10 and Hunt Hess 1-4 within 72 hours of presumed aneurysm rupture
Enrollment and initiation of nVNS treatment must occur within 72 hours of presumed aneurysm rupture
Provide a legally obtained informed consent form from the participant or the legally authorized representative (LAR); telephonic consent is acceptable
Female participants of reproductive age must have a negative pregnancy test result (urine or blood)

Exclusion Criteria

Use of any concomitant electrostimulation device, including a pacemaker, defibrillator, or deep brain stimulator
No plan to secure aneurysm, defined as aneurysm that has not been surgically or endovascularly treated
Previous neck dissection or radiation
History of carotid artery disease or carotid surgery/dissection
History of secondary or tertiary heart blocks, ventricular tachycardia, or supraventricular tachycardia (SVT; including atrial fibrillation)
Screws, metals, or devices in the neck
Currently participating in an investigational drug or device clinical trial with potential to confound data collection

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT05103566) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Subarachnoid Hemorrhage, Aneurysmal Treatment Options in Boston, MA

If you're searching for subarachnoid hemorrhage, aneurysmal treatment options in Boston, MA, this clinical trial (NCT05103566) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced subarachnoid hemorrhage, aneurysmal specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all subarachnoid hemorrhage, aneurysmal clinical trials near you to find additional studies recruiting in your area.

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