Charleston, SCNCT04199780Now EnrollingIRB Ready

Total Knee Arthroplasty (Postoperative Pain) Clinical Trial in Charleston, SC

Access cutting-edge total knee arthroplasty (postoperative pain) treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

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Expert Care in Charleston

Access total knee arthroplasty (postoperative pain) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related total knee arthroplasty (postoperative pain) treatment provided free

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Check if you qualify for this total knee arthroplasty (postoperative pain) clinical trial in Charleston, SC

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Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Total Knee Arthroplasty (Postoperative Pain) Study in Charleston

The purpose of this study is to determine whether a new medical technology can help reduce post-operative total knee or hip pain when combined with a Cognitive-Behavioral intervention (CBI). This new medical technology, is called transcranial direct current stimulation (tDCS), it uses a very small amount of electricity to temporarily stimulate specific areas of the brain thought to be involved in pain reduction. The electrical current passes through the skin, scalp, hair, and skull and requires no additional medication, sedation, or needles. This study will investigate the effects of tDCS, the Cognitive-Behavioral (CB) intervention and their combination on pain among veterans following total knee arthroplasty (TKA) or total hip arthroplasty (THA). The Veteran may benefit in the form of decreased pain and opioid requirements following knee or hip replacement surgery. However, benefit is only likely if Veterans are randomized to one of the 3 (out of 4) groups. This study hopes to determine the effects of these interventions and combined effect on post-operative pain, opioid use and functioning during the 48-hour post-operative period following a total knee or hip replacement.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

Participants will be 120 patients (132 recruited to account for 10% drop-out rate) undergoing TKA or THA surgery at the Ralph H. Johnson VAMC in Charleston SC.
Mentally capable of reading, writing, giving consent, and following instructions
Cleared for, and scheduled for unilateral TKA or THA surgery
Able to hear CB intervention and understand educational materials through headphones in English

Exclusion Criteria

implanted medical devices above the waist
history of seizures
allergic to latex rubber
psychiatric conditions except for depression and/or anxiety disorders (commonly seen in this population).

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT04199780) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Total Knee Arthroplasty (Postoperative Pain) Treatment Options in Charleston, SC

If you're searching for total knee arthroplasty (postoperative pain) treatment options in Charleston, SC, this clinical trial (NCT04199780) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced total knee arthroplasty (postoperative pain) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all total knee arthroplasty (postoperative pain) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC