Is NCT07849465 recruiting in Boise, ID?

Yes, NCT07849465 is currently recruiting participants at its Boise, ID location. This traumatic brain injury (tbi) patients clinical trial is actively enrolling qualified participants.

How do I join the traumatic brain injury (tbi) patients clinical trial in Boise?

To join this clinical trial in Boise, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Boise clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Traumatic Brain Injury (TBI) Patients Clinical Trial in Boise, ID

About This Traumatic Brain Injury (TBI) Patients Study in Boise

The goal of this study is to examine changes in blood biomarkers following hyperbaric oxygen therapy (HBOT) in military veterans with traumatic brain injury and persistent post-concussive symptoms. The main questions it aims to answer are: 1. Does HBOT produce measurable changes in inflammatory, neurotrophic, and neuronal injury biomarkers from baseline to completion of a 40-session treatment protocol in veterans with TBI and PCS? 2. Does the presence of comorbid PTSD influence biomarker responses to HBOT among veterans with TBI and PCS? Participants will: Complete medical and behavioral health evaluations to determine eligibility. Provide blood samples before treatment and after the final session. Receive 40 HBOT sessions at 2.0 ATA, generally two sessions per day with at least four hours between sessions. Approximately 34 veterans will participate. All participants will receive HBOT; there is no comparison group.

Sponsor: Summit Hyperbarics and Wellness

Who Can Participate

Inclusion Criteria

At least 18 years of age.

Veteran status

Clinically diagnosed with a TBI by a qualified healthcare professional.

Participants with comorbid post-traumatic stress disorder (PTSD), diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria by a qualified and trained professional, are eligible for enrollment but are not required for study participation. 4\. The participant is willing and able to read, understand, and sign an informed consent. Additionally, the participant has clear consciousness and the ability to express self-feelings independently. 6\. Completed psychological measurements (pre-study screening requirement) 7. Presence of clinically significant cognitive and/or PCS symptoms resulting in impairment in occupational, social, and other important areas of functioning, as determined by clinical evaluation. 8\. Sexually active female participants of childbearing potential and sexually active male participants with female partners of childbearing potential must agree to use an acceptable method of contraception for the duration of the study and for 30 days following the final HBOT session. 9\. Stability on any prescribed psychoactive medications and/or other chronic medical medications. Stability is defined as no significant changes in type of dosage within the previous 4-5 weeks, to minimize confounding effects on study outcomes and ensure participant safety.

Exclusion Criteria

Untreated pneumothorax

History of spontaneous pneumothorax

Asymptomatic pulmonary lesions on chest x-ray

Uncontrollable high fever (greater than 39C)

History of chest or ear surgery

Congenital spherocytosis

Any anemia or blood disorder

Any convulsive disorder

History of optic neuritis or sudden blindness

Middle ear infection

Diabetes mellitus (insulin therapy)

The participant is pregnant or lactating

Nicotine use/substance use/addiction

Acute Hypoglycemia

Diagnosed Chronic Obstructive Pulmonary Disease (COPD) and Emphysema

Presenting with symptoms of cough, congestion, vomiting, diarrhea, or open wounds.

Active malignancy

Current manic, delusional, or psychotic episodes

Serious/current suicidal ideations

Severe or unstable physical disorders or major cognitive deficits

Inability to attend scheduled clinic visits or comply with study protocols.

Treated with HBOT for any reason prior to study enrollment.

Non-English speakers

History of retinal repair, including laser photocoagulation or retinal detachment surgery.

History of middle ear surgery, including tympanoplasty, mastoidectomy, or pressure equalization tube placement.

Age greater than 75 years.

Use of any of the following medications during the study period: Anti-metabolites (e.g., methotrexate, azathioprine); Chemotherapeutic agents (e.g., cyclophosphamide, cisplatin); Mafenide acetate e.g., Sulfamylon); Disulfiram (e.g, Antabuse); Peripheral vasodilators known to interact with oxygen exposure (e.g., nitroglycerin); and Antibacterial drugs with known HBOT interaction risks.

Recent vaccination (≤ 1 week), or underlying inflammatory conditions

Use of systemic corticosteroids or immunomodulatory therapies

Active or recent infection requiring antibiotics.

Significant renal or hepatic impairment.

Regular participation in intense physical training or exercise programs (Defined as endurance events (e.g., triathlons, marathons, ultramarathons, Ironman-level training) or high-intensity interval training (HIIT) programs performed multiple times per week)

Recent (within 4 weeks prior to baseline) or planned use of antioxidant supplements or high-dose vitamins (Examples include: Vitamin C (\> 500 mg/day), Vitamin E (\>200 IU/day), N-acetylcysteine (NAC) or other thiol-based antioxidants, Alpha-lipoic acid, high-dose multivitamins containing the above doses, or Omega-3 fatty acid concentrates taken specifically for antioxidant/anti-inflammatory purposes)

Recent participation in other clinical trials that could affect biomarker levels.

Untreated or severe sleep disorders

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boise?

Yes, this clinical trial (NCT07849465) has an active research site in Boise, ID that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Traumatic Brain Injury (TBI) Patients Treatment Options in Boise, ID

If you're searching for traumatic brain injury (tbi) patients treatment options in Boise, ID, this clinical trial (NCT07849465) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boise research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced traumatic brain injury (tbi) patients specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all traumatic brain injury (tbi) patients clinical trials near you to find additional studies recruiting in your area.

Traumatic Brain Injury (TBI) Patients Clinical Trial in Boise, ID

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