Tucson, AZNCT07623135Now EnrollingIRB Ready

Treatment Resistant Depression (TRD) Clinical Trial in Tucson, AZ

Access cutting-edge treatment resistant depression (trd) treatment through this phase 3 clinical trial at a research site in Tucson. Study-provided care at no cost to qualified participants.

Sponsored by Eric Lenze

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Expert Care in Tucson

Access treatment resistant depression (trd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related treatment resistant depression (trd) treatment provided free

Apply for This Tucson Location

Check if you qualify for this treatment resistant depression (trd) clinical trial in Tucson, AZ

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Tucson

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Tucson site if eligible
  4. 4Begin participation

About This Treatment Resistant Depression (TRD) Study in Tucson

The purpose of this research study is to examine how well a medication called lumateperone (Caplyta) works to relieve depression in older adults with treatment-resistant depression. Lumateperone (Caplyta) is approved by the U.S. Food and Drug Administration to treat Major Depressive Disorder in adults who are also taking another antidepressant medication. This study will compare lumateperone (Caplyta) to placebo (a sugar pill without medication).

Sponsor: Eric Lenze

Who Can Participate

Inclusion Criteria

Current unipolar non-psychotic major depression determined by SCID-5
MADRS score \>=20 at screening and \>=18 at baseline
Treatment-resistance defined as documented history of non-response to at least two oral medications of adequate dose and duration in this episode or previous episode, OR clinician determination that treatment augmentation is appropriate
Currently taking oral antidepressant prescribed at least minimum therapeutic dose and for at least six weeks duration
MMSE score of \>/=24

Exclusion Criteria

High risk for suicide, defined as a 4 or 5 on C-SSRS (indicating active suicidal ideation with current or recent intent or plan), and unable to be managed safely in the clinical trial. Urgent psychiatric referral will be made in these cases.
High risk alcohol use: defined as a score of 6 or more on the AUDIT-C
Medically inappropriate for participation as determined by PIs.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Tucson?

Yes, this clinical trial (NCT07623135) has an active research site in Tucson, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Treatment Resistant Depression (TRD) Treatment Options in Tucson, AZ

If you're searching for treatment resistant depression (trd) treatment options in Tucson, AZ, this clinical trial (NCT07623135) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Tucson research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced treatment resistant depression (trd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all treatment resistant depression (trd) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Tucson, AZ