16 Active Studies

Stomach Cancer Clinical Trials

Find actively recruiting research studies for stomach cancer. Connect with study sites near you and explore new treatment options.

16
Active Trials
78+
Locations
4,132
Participants Needed

Recruiting Studies

RecruitingNCT06764875

A Phase â…¢ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

This is a Phase â…¢, randomized, open-label, Sponsor-blinded, 3-arm, global, multicenter study assessing the efficacy and safety of rilvegostomig in combination with fluoropyrimidine and T-DXd (Arm A) c...

10 locations(Anchorage, Phoenix, Duarte)
840 participants
AstraZeneca
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RecruitingNCT06172478

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

This is a proof-of-concept study designed to investigate HER3-DXd monotherapy in locally advanced unresectable or metastatic solid tumors. The study is enrolling cohorts of participants with melanoma ...

10 locations(Duarte, New Haven, Kissimmee)
740 participants
Daiichi Sankyo
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RecruitingNCT06532006

A Phase â…¢ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

This is a double-blind, randomized, multiregion, comparative phase â…¢ clinical study designed to evaluate the efficacy and safety of HLX22 in combination with trastuzumab and chemotherapy as first-line...

10 locations(Anaheim, Los Alamitos, Greeley)
550 participants
Shanghai Henlius Biotech
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RecruitingNCT06901531

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesophageal junction (GEJ) cancer. Zolbetuximab with che...

10 locations(Iowa City, Boston, Saint Louis Park)
500 participants
Astellas Pharma Global Development, Inc.
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RecruitingNCT04379596

Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)

DESTINY-Gastric03 will investigate the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of trastuzumab deruxtecan (T-DXd) alone or in combination with chemoth...

10 locations(Santa Monica, Westwood, Baltimore)
413 participants
AstraZeneca
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RecruitingNCT04248452

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric ca...

10 locations(Anchorage, Anchorage, Anchorage)
314 participants
ECOG-ACRIN Cancer Research Group
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RecruitingNCT06157892

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spre...

10 locations(Tucson, Tucson, Tucson)
172 participants
Seagen, a wholly owned subsidiary of Pfizer
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RecruitingNCT06038578

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

This study will assess the efficacy, safety, optimal dose and ADA and NAbs development of TRK-950 at two separate dose levels in combination with ramucirumab and paclitaxel (RAM+PTX) as compared with ...

10 locations(Duarte, Irvine, Santa Monica)
146 participants
Toray Industries, Inc
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RecruitingNCT03539822

Cabozantinib Plus Durvalumab with or Without Tremelimumab in Patients with Gastroesophageal Cancer and Other Gastrointestinal Malignancies

The investigators propose to evaluate the safety of drug combinations in patients with advanced gastroesophageal cancer and other gastrointestinal (GI) malignancies. Finding effective novel therapies ...

2 locations(Westwood, Pittsburgh)
117 participants
Anwaar Saeed
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RecruitingNCT04725994

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination with XELOX or Irinotecan in Patients with Advanced Gastric Cancer

This is an open-label, Phase 1b/2a study to evaluate the safety and tolerability of IDX-1197 and determine the MTD and RP2D in combination with XELOX or irinotecan in patients with advanced gastric ca...

10 locations(Los Angeles, Baton Rouge, Boston)
100 participants
Idience Co., Ltd.
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RecruitingNCT03259867

Combination of TATE and PD-1 Inhibitor in Liver Cancer

This is a multi-center, open-label phase IIA study that investigates the preliminary efficacy of Trans-arterial Tirapazamine Embolization (TATE) treatment of liver cancer followed by a PD-1 checkpoint...

3 locations(Orange, Oklahoma City, Milwaukee)
54 participants
Teclison Ltd.
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RecruitingNCT06123338

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

The purpose of this study to find out whether adding trastuzumab and pembrolizumab to standard chemotherapy is an effective treatment for resectable HER2+ esophagogastric cancer....

10 locations(Boston, Basking Ridge, Middletown)
49 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNCT04656041

Folfox+Irinotecan+Chemort In Esophageal Cancer

In this research study, is studying how Liposomal Irinotecan in combination with the standard of care interventions FOLFOX, carboplatin paclitaxel, and radiation therapy affect gastroesophageal juncti...

3 locations(Boston, Boston, Newton)
40 participants
Massachusetts General Hospital
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RecruitingNCT02366819

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

This pilot clinical trial studies genetic analysis-guided irontecan hydrochloride dosing of modified fluorouracil, irinotecan hydrochloride, leucovorin calcium, oxaliplatin (mFOLFIRINOX) in treating p...

3 locations(Chicago, Evanston, Evanston)
36 participants
University of Chicago
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RecruitingNCT06116136

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

This study will investigate the safety, tolerability, and antitumor activity of S095029 (anti-NKG2A antibody) in combination with pembrolizumab in in microsatellite instability-high/Defective mismatch...

10 locations(Ocala, Noblesville, Houston)
32 participants
Servier Bio-Innovation LLC
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RecruitingNCT04308837

A Phase II Trial of Neoadjuvant Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Chemoradiation

Stomach cancer is the fifth most common digestive cancer and third main cause of death from cancer in the world. Modern management of Gastric cancer involves a multi-disciplinary approach involving su...

3 locations(New York, New York, New York)
29 participants
Icahn School of Medicine at Mount Sinai
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Frequently Asked Questions

What clinical trials are available for Stomach Cancer?

There are currently 16 actively recruiting clinical trials for stomach cancer. These studies are testing new treatments, therapies, and interventions at research sites across 78 cities.

How do I join a Stomach Cancer clinical trial?

To join a stomach cancer clinical trial: 1) Browse the available studies above, 2) Click on a study that interests you, 3) Complete the eligibility form, and 4) A study coordinator will contact you.

Are clinical trials free for patients?

Yes, clinical trial participation is free. In most studies, the treatment, medical tests, and doctor visits related to the trial are provided at no cost. Some studies may also compensate for time and travel.

Can I leave a clinical trial if I change my mind?

Yes, participation in any clinical trial is completely voluntary. You can withdraw at any time, for any reason, without affecting your regular medical care.