Baltimore, MD5 Active Studies

Head and Neck Cancer Clinical Trials in Baltimore, MD

Find 5 actively recruiting head and neck cancer clinical trials in Baltimore, MD. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
1,053
Enrolling

Recruiting Head and Neck Cancer Studies in Baltimore

RecruitingBaltimore, MDNCT06790966

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

This is a global, multi-center, Phase 3 study that is randomized 2:1, controlled, and open label to evaluate PDS0101 (Versamune + HPVMix) in combination with pembrolizumab vs. pembrolizumab monotherap...

351 participants
PDS Biotechnology Corp.
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RecruitingBaltimore, MDNCT06385080

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer

The purpose of this study is to determine safety and preliminary efficacy of amivantamab monotherapy, amivantamab in addition to pembrolizumab, amivantamab in addition to paclitaxel and amivantamab in...

247 participants
Janssen Research & Development, LLC
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RecruitingBaltimore, MDNCT04915183

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of...

224 participants
National Institute on Deafness and Other Communication Disorders (NIDCD)
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RecruitingBaltimore, MDNCT05966194

RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer

The purpose of this study is to determine if RRx-001, which is added on to the cisplatin and radiation treatment, reduces the incidence of severe oral mucositis in patients with head and neck cancers....

216 participants
EpicentRx, Inc.
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RecruitingBaltimore, MDNCT05977907

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

This research is being done to see if it is safe to give investigational combination of study drugs (Pembrolizumab and IO102-103) before surgery to people with surgically resectable (removable) newly ...

15 participants
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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About Head and Neck Cancer Clinical Trials in Baltimore

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 5 head and neck cancer clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 1,053 participants. Research is being sponsored by PDS Biotechnology Corp., Janssen Research & Development, LLC, National Institute on Deafness and Other Communication Disorders (NIDCD) and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Baltimore — FAQ

Are there head and neck cancer clinical trials in Baltimore?

Yes, there are 5 head and neck cancer clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 5 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated March 2, 2026 from ClinicalTrials.gov