7 Head and Neck Cancer Clinical Trials in Baltimore, MD (2026)

Q: How do I join a clinical trial in Baltimore?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you.

Recruiting Head and Neck Cancer Studies in Baltimore

NCT05337631Recruiting

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is li...

Baltimore, MD1,500 participantsUniversity Hospital Freiburg

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NCT05995821Recruiting

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect ...

Baltimore, MD1,250 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT06385080Recruiting

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Recurrent/Metastatic Head and Neck Cancer

The purpose of this study is to determine safety and preliminary efficacy of amivantamab monotherapy, amivantamab in addition to pembrolizumab, amivantamab in addition to paclitaxel and amivantamab in...

Baltimore, MDPHASE1287 participantsJanssen Research & Development, LLC

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NCT04915183Recruiting

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of...

Baltimore, MDPHASE2224 participantsNational Institute on Deafness and Other Communication Disorders (NIDCD)

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NCT07209189Recruiting

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

The NeoScorch HN study is a single institution multisite phase II trial including 3 cohorts of 25 patients each for patients with newly diagnosed locoregionally advanced, histologically confirmed, hea...

Baltimore, MDPHASE275 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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NCT05172245Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients ...

Baltimore, MDPHASE146 participantsNational Cancer Institute (NCI)

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NCT05977907Recruiting

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

This research is being done to see if it is safe to give investigational combination of study drugs (Pembrolizumab and IO102-103) before surgery to people with surgically resectable (removable) newly ...

Baltimore, MDPHASE230 participantsSidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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About Head and Neck Cancer Clinical Trials in Baltimore

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 7 head and neck cancer clinical trials recruiting participants in Baltimore, MD. These studies are seeking a combined 3,412 participants. Research is being sponsored by University Hospital Freiburg, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Janssen Research & Development, LLC and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Baltimore — FAQ

Are there head and neck cancer clinical trials in Baltimore?

Yes, there are 7 head and neck cancer clinical trials currently recruiting in Baltimore, MD. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Baltimore?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Baltimore research site will contact you about next steps.

Are clinical trials in Baltimore free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Baltimore studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 7 active trials in Baltimore are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated July 21, 2026 from ClinicalTrials.gov