11 Spinal Cord Injury Clinical Trials in Boston, MA (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Spinal Cord Injury Studies in Boston

NCT04712812Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or sa...

Boston, MA700 participantsBoston Children's Hospital

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NCT05354622Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders. The HSPs are a group of more than 80 inherited n...

Boston, MA200 participantsBoston Children's Hospital

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NCT06568536Recruiting

Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU

Disorders of consciousness (DoC) caused by severe brain injury affect millions of people worldwide each year. A patient's level of consciousness in the intensive care unit (ICU) significantly impacts ...

Boston, MANA120 participantsMassachusetts General Hospital

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NCT06553976Recruiting

Spastic Paraplegia - Centers of Excellence Research Network

The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diagnosis, and treatment of hereditary spasti...

Boston, MA100 participantsBoston Children's Hospital

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NCT05010265Recruiting

An Ethical Approach to Detecting Covert Consciousness

This study aims to develop an ethical approach to developing and deploying novel neurotechnologies to aid in the detection of consciousness and prediction of recovery after brain injury....

Boston, MA70 participantsMassachusetts General Hospital

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NCT06939348Recruiting

Ultrasound Stimulation for Patients in a Disorder of Consciousness

The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this multicenter project aims ...

Boston, MANA60 participantsUniversity of California, Los Angeles

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NCT07277309Recruiting

Promoting Recovery After Brain Injury Using Focused Ultrasound

The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this project aims to (1) deter...

Boston, MANA36 participantsMassachusetts General Hospital

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NCT00912041Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and...

Boston, MANA27 participantsLeigh R. Hochberg, MD, PhD.

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NCT05324579Recruiting

Studying the Neuronal Basis of Human Social Cognition

This proposal aims to study the role that the dorsal prefrontal cortex plays in human social cognition....

Boston, MANA20 participantsMassachusetts General Hospital

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NCT03311503Recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 with Low Dose Targeted Busulfan Conditioning

This is a phase I/II open label multi-center study in which patients will receive low dose targeted busulfan followed by infusion of autologous CD34+ selected bone marrow or mobilized peripheral blood...

Boston, MAPHASE112 participantsDavid Williams

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NCT07228286Recruiting

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

The RE-CONNECT study is an early feasibility study to establish the safety, feasibility, and efficacy of two central thalamic deep brain stimulation targets in patients with chronic disorders of consc...

Boston, MAEARLY_PHASE12 participantsSamuel Snider, MD

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About Spinal Cord Injury Clinical Trials in Boston

Spinal cord injury is damage to the spinal cord that causes loss of function, mobility, or sensation below the injury site. It can result in paraplegia or quadriplegia depending on the level of injury. Research is exploring regenerative therapies, electrical stimulation, and rehabilitation technologies.

There are currently 11 spinal cord injury clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 1,347 participants. Research is being sponsored by Boston Children's Hospital, Massachusetts General Hospital, University of California, Los Angeles and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Spinal Cord Injury Clinical Trials in Boston — FAQ

Are there spinal cord injury clinical trials in Boston?

Yes, there are 11 spinal cord injury clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What spinal cord injury treatments are being tested?

The 11 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for spinal cord injury.

Data updated July 18, 2026 from ClinicalTrials.gov