4 Colorectal Cancer Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Colorectal Cancer Studies in Durham

NCT06885034Recruiting

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed

This study will check how well a new medicine, GSK5764227, works, how safe it is and how the body handles it in participants all around the world with advanced inoperable or metastatic gastrointestina...

Durham, NCPHASE1451 participantsGlaxoSmithKline

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NCT07127874Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012, a novel antibody-drug conjugate (ADC), in patients ...

Durham, NCPHASE1165 participantsPheon Therapeutics

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NCT05848739Recruiting

A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST316 administered IV in subjects with sele...

Durham, NCPHASE1130 participantsSapience Therapeutics

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NCT07235293Recruiting

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

This clinical study is testing whether a new combination of medicines (DSP107 and atezolizumab) is more effective and safer than an existing treatment (fruquintinib) for people with advanced colorecta...

Durham, NCPHASE290 participantsKahr Bio Australia Pty Ltd

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About Colorectal Cancer Clinical Trials in Durham

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 4 colorectal cancer clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 836 participants. Research is being sponsored by GlaxoSmithKline, Pheon Therapeutics, Sapience Therapeutics and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Durham — FAQ

Are there colorectal cancer clinical trials in Durham?

Yes, there are 4 colorectal cancer clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 4 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated July 18, 2026 from ClinicalTrials.gov