4 Melanoma Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Melanoma Studies in Durham

NCT03947385Recruiting

Study of IDE196 in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

This is a Phase 1/2, multi-center, open-label basket study designed to evaluate the safety and anti-tumor activity of IDE196 in patients with solid tumors harboring GNAQ or GNA11 (GNAQ/11) mutations o...

Durham, NCPHASE1336 participantsIDEAYA Biosciences

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NCT05839912Recruiting

Excision of Lymph Node Trial (EXCILYNT) (Mel69)

The purpose of this study is to find out if removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing cancer from coming back in the same area of the lymph nod...

Durham, NCNA66 participantsCraig L Slingluff, Jr

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NCT05077137Recruiting

A Feasibility Study Utilizing Immune Recall to Increase Response to Checkpoint Therapy

The purpose of this study is to determine the safety and feasibility of administering the Tetanus Diptheria Vaccine (Td) or Polio Boost Immunization (IPOL) to patients with metastatic melanoma who are...

Durham, NCPHASE125 participantsDuke University

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NCT07237594Recruiting

IL-17 Blockade to Decrease irAEs (REPLAY)

The primary objective of this study is to determine the safety and feasibility of administering an IL-17A (human IgG1κ) monoclonal antibody, (Secukinumab, Cosentyx®) to participants with metastatic me...

Durham, NCPHASE14 participantsDuke University

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About Melanoma Clinical Trials in Durham

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 4 melanoma clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 431 participants. Research is being sponsored by IDEAYA Biosciences, Craig L Slingluff, Jr, Duke University. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Durham — FAQ

Are there melanoma clinical trials in Durham?

Yes, there are 4 melanoma clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 4 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated July 18, 2026 from ClinicalTrials.gov