Recruiting Myeloproliferative Neoplasms Studies in Durham
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
This is a study evaluating the safety and efficacy of bomedemstat (MK-3543) compared with the best available therapy (BAT) in participants with essential thrombocythemia (ET) who have an inadequate re...
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
The purpose of this study is to evaluate the efficacy and safety of bomedemstat compared with hydroxyurea in cytoreductive therapy naïve essential thrombocythemia (ET) participants for whom cytoreduct...
A Study of Selinexor Monotherapy in Subjects with JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia
The main purpose of this study with corresponding optional expansion is to evaluate the efficacy of selinexor in JAKi-naïve participants with myelofibrosis (MF) and moderate thrombocytopenia based on ...
Study to Assess SLN124 in Patients With Polycythemia Vera
This is a Phase 1/2, multicenter study with an open-label dose escalation followed by a randomized placebo controlled and double-blind phase of SLN124 in adult patients with Polycythemia Vera (PV) to ...
About Myeloproliferative Neoplasms Clinical Trials in Durham
Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.
There are currently 4 myeloproliferative neoplasms clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 783 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Karyopharm Therapeutics Inc, Silence Therapeutics plc. Clinical trial participation is free and participants receive study-related medical care at no cost.
Myeloproliferative Neoplasms Clinical Trials in Durham — FAQ
Are there myeloproliferative neoplasms clinical trials in Durham?
Yes, there are 4 myeloproliferative neoplasms clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Durham?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.
Are clinical trials in Durham free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.
What myeloproliferative neoplasms treatments are being tested?
The 4 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.
Data updated March 2, 2026 from ClinicalTrials.gov