17 Head and Neck Cancer Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Head and Neck Cancer Studies in New York

NCT05337631Recruiting

Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy

The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is li...

New York, NY1,500 participantsUniversity Hospital Freiburg

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NCT05053230Recruiting

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

The overarching long-term goal of the Integrative Medicine for Patient-reported Outcomes Values and Experience (IMPROVE) research program is to evaluate whether integrating a virtual mind-body program...

New York, NYNA324 participantsMemorial Sloan Kettering Cancer Center

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NCT06563479Recruiting

A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer

The researchers are doing this study to find out if a personalized approach to chemoradiation therapy (which may include a lower dose of radiation) is as effective as the standard chemoradiation thera...

New York, NYPHASE3291 participantsMemorial Sloan Kettering Cancer Center

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NCT06030011Recruiting

Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations

The PI and the research team developed the New York University (NYU) Electronic Patient Visit Assessment (ePVA) for head and neck cancer (HNC) as a patient-reported outcome measure (PRO) for the early...

New York, NYNA270 participantsThe University of Texas Health Science Center, Houston

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NCT03483337Recruiting

New MRI Biomarkers in Head and Neck Cancers

Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes specific organs, blood ves...

New York, NY200 participantsMemorial Sloan Kettering Cancer Center

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NCT02507141Recruiting

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

The purpose of this study is to get images (pictures) of oral lesions, which occur inside the mouth, before the patient's surgery using a special camera. These pictures will be used in our research to...

New York, NY140 participantsMemorial Sloan Kettering Cancer Center

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NCT05491512Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

The purpose of this study is to find out if lower doses of radiation may help reduce the side effects of radiation therapy in combination with standard-of-care chemotherapy in people with HPV-positive...

New York, NYPHASE2121 participantsMemorial Sloan Kettering Cancer Center

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NCT03215719Recruiting

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

This is a phase II clinical trial. The purpose of this study is to determine the feasibility of deescalating chemoradiation treatment based on mid-treatment tumor response determined by rapid nodal sh...

New York, NYPHASE2120 participantsNYU Langone Health

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NCT05952934Recruiting

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

This is a Phase II randomized, double-blind, placebo controlled, multi-site study of Candin. It is designed to show the efficacy and safety of a 7-dose regimen of Candin over a two-year period in term...

New York, NYPHASE2100 participantsUniversity of Arkansas

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NCT06457503Recruiting

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....

New York, NYPHASE4100 participantsCoherus Oncology, Inc.

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NCT05419089Recruiting

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

The purpose of this study is to determine whether treatment of HPV-related oropharyngeal squamous cell carcinoma in patients with undetectable postoperative HPV circulating tumor DNA (cfHPVDNA) with t...

New York, NYPHASE283 participantsIcahn School of Medicine at Mount Sinai

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NCT07095608Recruiting

Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain

This is a prospective study involving human participants. Pressure and stretch sensitivity measures between oral cancer patients and healthy subjects will be compared. Pain stimulation will be conduct...

New York, NYNA80 participantsNew York University

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NCT06984861Recruiting

A Study of Reduced Radiation Therapy With Chemotherapy in People With HPV-Positive Throat Cancer

The researchers are doing this study is to find out if lower doses (given in fewer treatments over a shorter period of time) of radiation therapy in combination with standard-of-care chemotherapy is a...

New York, NYPHASE274 participantsMemorial Sloan Kettering Cancer Center

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NCT05207098Recruiting

A Study of Neurocognitive Tests and Questionnaires for People With Head and Neck Cancer Who Are Undergoing Radiation Therapy

The researchers are doing this study to collect more information about if, and how, neurocognitive function may be affected in people being treated with radiation therapy for head and neck cancer. Par...

New York, NY60 participantsMemorial Sloan Kettering Cancer Center

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NCT04722523Recruiting

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

The purpose of this study is to find out whether combining the standard chemotherapy for head and neck cancer with the immunotherapy drugs cetuximab and cemiplimab (the study drug) is a safe treatment...

New York, NYPHASE140 participantsMemorial Sloan Kettering Cancer Center

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NCT07063212Recruiting

A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

The purpose of this study to find out whether sacituzumab govitecan in combination with cetuximab is an effective and safe treatment approach for people with recurrent and/or metastatic head and neck ...

New York, NYPHASE240 participantsMemorial Sloan Kettering Cancer Center

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NCT05544136Recruiting

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

The purpose of this study is to test the treatment approach of de-escalated radiation and chemotherapy followed by a planned neck dissection surgery in people with head and neck cancer. The study will...

New York, NYPHASE212 participantsMemorial Sloan Kettering Cancer Center

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About Head and Neck Cancer Clinical Trials in New York

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 17 head and neck cancer clinical trials recruiting participants in New York, NY. These studies are seeking a combined 3,555 participants. Research is being sponsored by University Hospital Freiburg, Memorial Sloan Kettering Cancer Center, The University of Texas Health Science Center, Houston and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in New York — FAQ

Are there head and neck cancer clinical trials in New York?

Yes, there are 17 head and neck cancer clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 17 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated July 19, 2026 from ClinicalTrials.gov