3 Esophageal Cancer Clinical Trials in Orange, CA (2026)

Q: How do I join a clinical trial in Orange?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you.

Recruiting Esophageal Cancer Studies in Orange

NCT07221149Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

The purpose of this study is to evaluate the safety and efficacy of Pumitamig in combination with chemotherapy versus Nivolumab in combination with chemotherapy in participants with previously untreat...

Orange, CA690 participantsBristol-Myers Squibb

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NCT07284186Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

A multicenter, single-arm, first-in-human study to investigate the safety, pharmacokinetics, and preliminary antitumor activity of PLX-61639 in participants with locally advanced or metastatic, relaps...

Orange, CA155 participantsPlexium, Inc.

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NCT05733689Recruiting

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

This is a phase 1b prospective, single arm, open-label trial determining the efficacy and feasibility of using a response-guided approach to help guide neoadjuvant chemotherapy in subjects with Stage ...

Orange, CA20 participantsUniversity of California, Irvine

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About Esophageal Cancer Clinical Trials in Orange

Esophageal cancer occurs in the esophagus, the tube connecting the throat to the stomach. The two main types are squamous cell carcinoma and adenocarcinoma. Treatment may include surgery, chemotherapy, radiation, and immunotherapy.

There are currently 3 esophageal cancer clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 865 participants. Research is being sponsored by Bristol-Myers Squibb, Plexium, Inc., University of California, Irvine. Clinical trial participation is free and participants receive study-related medical care at no cost.

Esophageal Cancer Clinical Trials in Orange — FAQ

Are there esophageal cancer clinical trials in Orange?

Yes, there are 3 esophageal cancer clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What esophageal cancer treatments are being tested?

The 3 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for esophageal cancer.

Data updated July 13, 2026 from ClinicalTrials.gov