Recruiting Head and Neck Cancer Studies in Orlando
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
This is a Phase 3 randomized, open-label study to evaluate the efficacy and safety of petosemtamab plus pembrolizumab vs pembrolizumab in first-line treatment of recurrent or metastatic PD-L1+ head an...
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
The purpose of this study is to compare the efficacy and safety of ficlatuzumab plus cetuximab compared to placebo plus cetuximab in participants with recurrent/metastatic (R/M) HPV-negative Head and ...
Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
This is a global, multi-center, Phase 3 study that is randomized 2:1, controlled, and open label to evaluate PDS0101 (Versamune + HPVMix) in combination with pembrolizumab vs. pembrolizumab monotherap...
About Head and Neck Cancer Clinical Trials in Orlando
Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.
There are currently 3 head and neck cancer clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 1,261 participants. Research is being sponsored by Merus N.V., AVEO Pharmaceuticals, Inc., PDS Biotechnology Corp.. Clinical trial participation is free and participants receive study-related medical care at no cost.
Head and Neck Cancer Clinical Trials in Orlando — FAQ
Are there head and neck cancer clinical trials in Orlando?
Yes, there are 3 head and neck cancer clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Orlando?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.
Are clinical trials in Orlando free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.
What head and neck cancer treatments are being tested?
The 3 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.
Data updated March 2, 2026 from ClinicalTrials.gov