Access cutting-edge depression treatment through this phase 2 clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.
Quick Self-Assessment
See if you qualify for this St Louis location
Preparing your pre-screening questions…
Access depression specialists at no cost
This study follows strict safety protocols and ethical guidelines
All study-related depression treatment provided free
Check if you qualify for this depression clinical trial in St Louis, MO
No-Cost Study Care
Local to St Louis
Convenient for MO residents
Cutting-Edge Treatment
Access to innovative therapies
Expert Medical Care
Close monitoring by specialists
Possible Compensation*
For time and travel
*Compensation varies by study. Confirm details with coordinator.
The investigators hypothesize that brief behavioral therapy and targeted propofol infusion in depressed geriatric patients will augment subsequent slow wave sleep and improve clinical and cognitive outcomes. The team will recruit 70 participants for a double-blinded placebo controlled randomized controlled trial. Two propofol infusions, 2-6 days apart, will be administered, targeting either a low propofol dose arm (minimal EEG slow waves, brain effect-site concentration 1-2 mcg/ml) or moderate dose propofol arm (maximal induction of EEG slow waves, brain effect site concentration of \>2.5 mcg/ml). The pharmacologic intervention will be paired with 3-4 sessions of Brief Behavioral Therapy for Insomnia for all participants. To minimize bias, there will be no specific gender or ethnic background consideration for enrollment. This will be a single site investigation at Washington University Medical Center.
Sponsor: Washington University School of Medicine
Yes, this clinical trial (NCT06867549) has an active research site in St Louis, MO that is currently enrolling participants.
Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.
Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.
Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.
If you're searching for depression treatment options in St Louis, MO, this clinical trial (NCT06867549) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.
Our St Louis research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.
Looking for more options? Browse all depression clinical trials near you to find additional studies recruiting in your area.
See all depression clinical trials recruiting in St Louis — not just this study.
Browse Depression Trials in St Louis →