Is NCT04141878 recruiting in Walnut Creek, CA?

Yes, NCT04141878 is currently recruiting participants at its Walnut Creek, CA location. This diabetes clinical trial is actively enrolling qualified participants.

How do I join the diabetes clinical trial in Walnut Creek?

To join this clinical trial in Walnut Creek, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Walnut Creek clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Diabetes Clinical Trial in Walnut Creek, CA

About This Diabetes Study in Walnut Creek

This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in intensity and format: 1. Aerobic Exercise (AEx) Intervention that involves aerobic activities with in-class walking workouts and tutorials and carried out at the East Oakland Sports Center (EOSC) and Tice Creek Fitness Center (TICE). 2. Dietary counseling to support adherence to the Mediterranean-Diet Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet to encourage increased consumption of berries, green leafy and other vegetables, whole grains, nuts, fish, poultry, beans and olive oil, and to reduce consumption of fried/fast foods, red meat, whole fat cheese, sweets, butter and trans-fat margarines.

Sponsor: University of California, Davis

Who Can Participate

Inclusion Criteria

Sedentary (as per the Telephone Assessment of Physical Activity)

Poor diet (as per the MIND Diet Screener)

Cognitive function: absence of significant cognitive impairment as per the modified Telephone Interview for Cognitive Status (TICSm; age-, education-, and race-adjusted TICSm \>32)

Lives in a region where the DDPP interventions will be delivered

Does not plan to travel outside of the home geographic area for more than 3 months over the course of the study

Free of physical disabilities that preclude participation in the study

Willing to complete all study-related activities for 32 weeks

Willing to be randomized to either lifestyle intervention group

Exclusion Criteria

Body Mass Index (BMI) \>40

Any significant neurologic disease, including any form of dementia, Parkinson's disease, Huntington's disease, normal pressure hydrocephalus, brain tumor, progressive supranuclear palsy, seizure disorder, subdural hematoma, multiple sclerosis, or history of significant head trauma with persistent neurologic sequelae or known structural brain abnormalities

History of major depression within the last 12 months

History of bipolar disorder or schizophrenia as per Diagnostic and Statistical Manual of Mental Disorders (DSM) V criteria

History of alcohol or substance abuse or dependence within the past 2 years, as per DSM V criteria

Use of psychoactive medications within the last 3 months including tricyclic antidepressants, antipsychotics, mood-stabilizing psychotropic agents (e.g., lithium salts), psychostimulants, opiate analgesics, antiparkinsonian medications, anticonvulsant medications (except gabapentin and pregabalin for non-seizure indications), systemic corticosteroids, or medications with significant central anticholinergic activity; in the absence of major depression, stable dose use of selective serotonin reuptake inhibitors or serotonin and norepinephrine reuptake inhibitors are allowed

Health profiles that would jeopardize their safety to participate: (Screen failures will be referred immediately to a physician for medical examination): (1) Myocardial infarction or symptoms of unstable coronary artery disease (e.g., angina) in the last six months, (2) Uncontrolled hypertension within the past 6 months, (3) Morbid obesity (BMI\<40), (4) History of clinically-evident stroke, (5) Clinically-significant infection within the past 30 days, (6) Significant pain or musculoskeletal disorder limiting the ability to participate safely, or (7) Clinically significant

Past or current use of insulin to treat type 2 diabetes

Serious diabetic event within 6 months of enrollment

Lung disease requiring either regular use of corticosteroids or the use of supplemental oxygen (inhaled steroids for asthma is permissible)

Renal disease

Clinically significant abnormalities in laboratory blood tests as per judgment of the Study Physician

History within the last 2 years of treatment for primary or recurrent malignant disease, excluding non-melanoma skin cancers, resected cutaneous squamous cell carcinoma in situ, basal cell carcinoma, cervical carcinoma in situ, or in situ prostate cancer with normal prostate-specific antigen post-treatment

History of hip fracture, joint replacement, or spinal surgery in the last 6 months

Currently receiving physical therapy or cardiopulmonary rehabilitation

History of a malabsorptive bariatric procedure (gastric bypass, biliopancreatic diversion); other bariatric procedures involving restriction (i.e., sleeve, band) are not exclusionary

For women: currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 6 months

Currently incarcerated

Receiving hospice care

Adults unable to provide consent for participation

PI/Study Physician discretion regarding appropriateness of participation or concern about intervention adherence

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Walnut Creek?

Yes, this clinical trial (NCT04141878) has an active research site in Walnut Creek, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Diabetes Treatment Options in Walnut Creek, CA

If you're searching for diabetes treatment options in Walnut Creek, CA, this clinical trial (NCT04141878) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Walnut Creek research site is actively enrolling participants for this clinical trial. You'll receive care from experienced diabetes specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all diabetes clinical trials near you to find additional studies recruiting in your area.

Diabetes Clinical Trial in Walnut Creek, CA

Expert Care in Walnut Creek

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