NCT05479461 · Stanford University
Technology-enabled Management Versus Usual Care for Blood Pressure
(HrtEx)
What this study is about
Two treatment group$1 parallel randomly assigned clinical trial
View original scientific description
Two arm parallel randomized clinical trial
Interventions
OTHER
Digital Hypertension Management System
Mobile health technology using physician- directed, semi-automated management of hypertension
OTHER
Usual Care
The participants will receive usual care
Primary outcome measures
Defined Daily Dose (DDD)
Time frame: Visit 1 (Baseline), Visit-3 (6 Month follow up)
Change in defined daily dose (DDD)
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Age 30-90 yrs.
- Smartphone ownership
- Office SBP: ≥ 140 mm Hg
- ≤ 2 current anti-HTN meds
- Able to add or dose-increase at least 2 of the following classes of medications: ACE-I/ARB, diuretic, calcium channel blocker, beta-blocker, mineralocorticoid receptor antagonists (i.e., at least 2 classes are available for addition or dose- increases after excluding intolerant medications and medications currently at maximum dose)
- English or Spanish-speakers
Exclusion criteria
- Heart failure with reduced ejection fraction (EF \< 40%)
- ESRD (GFR \<15)
- Renal replacement therapy
- Myocardial infarction or stroke within preceding 6 months
- Hospitalization for hypertensive emergency or malignant hypertension within preceding 6 months
- Prior solid organ transplantation
- At the clinical discretion of the investigators
- Enrolled in another clinical study
Where
- Palo Alto, California
- Atlanta, Georgia
- Eatonton, Georgia
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 11, 2025 · Source of record for eligibility and locations