New York, NYNCT07139834Now EnrollingIRB Ready

Major Depressive Disorder (MDD) Clinical Trial in New York, NY

Access cutting-edge major depressive disorder (mdd) treatment through this phase 1 clinical trial at a research site in New York. Study-provided care at no cost to qualified participants.

Sponsored by Jeffrey Miller

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in New York

Access major depressive disorder (mdd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder (mdd) treatment provided free

Apply for This New York Location

Check if you qualify for this major depressive disorder (mdd) clinical trial in New York, NY

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to New York

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit New York site if eligible
  4. 4Begin participation

About This Major Depressive Disorder (MDD) Study in New York

This study seeks to examine the effects of treatment with a selective serotonin reuptake inhibitor (SSRI), escitalopram, a first-line treatment for depression, in combination with placebo or with extended-release memantine, on neuropsychological function, regional brain activity assessed by functional magnetic resonance imaging, and depressive symptoms, in participants with Major Depressive Disorder. Escitalopram is administered in an open-label fashion in this study; extended release memantine is administered in a double-blind, randomized, placebo-controlled manner.

Sponsor: Jeffrey Miller

Who Can Participate

Inclusion Criteria

Current diagnosis of MDD without psychotic features assessed within three weeks of study enrollment
17-item Hamilton Depression Rating Scale score ≥17 assessed within 3 weeks of study enrollment
Using an effective form of contraception at study enrollment and agrees to continue throughout study participation for individuals of child-bearing potential
Capacity to provide informed consent
Proficient in English
Willing to provide emergency contact

Exclusion Criteria

Currently taking an antidepressant medication at study enrollment
Pregnant or breastfeeding at time of enrollment
Evidence of current unstable medical illness, including liver or renal impairment, or unstable cardiovascular or respiratory illness
QTc interval greater than 500 ms
Current genitourinary conditions that raise urine pH such as a) renal tubular acidosis or b) severe infection of the urinary tract.
Clinically significant neurological conditions, including a) history of stroke, b) previous head injury with evidence of cognitive impairment, c) history of malignancy or d) history of seizure disorder. (headache, migraines, pain disorders, and other conditions not exclusionary)
Lifetime diagnosis of a) bipolar disorder, b) psychotic disorder, or c) dementia
Current active suicidal ideation
Current substance use disorder other than tobacco use disorder
Current or recent (past 6 months) treatment with antipsychotics; current or recent (past 1 month) treatment with benzodiazepines; current use of prescribed stimulant medication; current use of other NMDA antagonists (amantadine, ketamine, dextromethorphan)
Current use of disulfiram with oral concentrate, MAOIs (including linezolid or IV methylene blue), or pimozide
History of hypersensitivity or allergic reaction to a) memantine hydrochloride or any of its components/excipients, b) citalopram, escitalopram, or any other component of the product, or c) sertraline or any other component of the product
Concurrent or recent (past 6 months) participation in another clinical trial for mental illness involving an investigational product or device
Lack of response to or intolerable side-effects from trials of two or more selective serotonin reuptake inhibitors of adequate dose and duration at study enrollment
Electroconvulsive therapy (ECT) in the past 6 months
Any condition or material in the body that is a contraindication for MRI procedures
Weight that exceeds 300 lbs or inability to fit into MRI scanner
MST LDI score greater than 0.5

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in New York?

Yes, this clinical trial (NCT07139834) has an active research site in New York, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder (MDD) Treatment Options in New York, NY

If you're searching for major depressive disorder (mdd) treatment options in New York, NY, this clinical trial (NCT07139834) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our New York research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced major depressive disorder (mdd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder (mdd) clinical trials near you to find additional studies recruiting in your area.

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