Philadelphia, PANCT07159061Now EnrollingIRB Ready

Major Depressive Disorder (MDD) Clinical Trial in Philadelphia, PA

Access cutting-edge major depressive disorder (mdd) treatment through this clinical trial at a research site in Philadelphia. Study-provided care at no cost to qualified participants.

Sponsored by University of Pennsylvania

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Expert Care in Philadelphia

Access major depressive disorder (mdd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder (mdd) treatment provided free

Apply for This Philadelphia Location

Check if you qualify for this major depressive disorder (mdd) clinical trial in Philadelphia, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Philadelphia

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Philadelphia site if eligible
  4. 4Begin participation

About This Major Depressive Disorder (MDD) Study in Philadelphia

This study tests the efficacy of a new psychotherapeutic strategy for reducing negative attention bias (and therefore depression severity) in participants with MDD. This real-time fMRI neurofeedback therapy uses cloud-based pattern classification to decode a patient's attentional state and dynamically modulate task stimuli (in a closed loop) based on this state.

Sponsor: University of Pennsylvania

Who Can Participate

Inclusion Criteria

Gender, inclusive
Adult aged 18 - 65
Meets Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for MDD according to the Clinician-Administered MDD Scale for DSM-5 (unipolar depression or bipolar II depressed)
Scores at least a minimum score of 16 on Montgomery Asberg Depression Rating Scale (MADRS)
Normal cognition
Participants must be able to read and understand English
Participants must be able to provide consent

Exclusion Criteria

Pregnancy (female participants)
Outside age range
MRI contraindications (medical implant, claustrophobia, etc.)
Use of psychoactive medication (including antidepressants) or currently in therapy
Neurological disorder or any condition that in the view of the PI could impact brain data, cause depression, require medication that could cause depressive symptoms, or otherwise result in participant being unfit for study (for example, co-morbid psychotic, neurological disorders, developmentally or cognitively disabled/impaired, active alcohol or drug abuse/dependence within the past 6 months).
Non-English speaking
Non-correctable vision loss
Refusal to provide informed consent
representing an active suicide risk

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Philadelphia?

Yes, this clinical trial (NCT07159061) has an active research site in Philadelphia, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder (MDD) Treatment Options in Philadelphia, PA

If you're searching for major depressive disorder (mdd) treatment options in Philadelphia, PA, this clinical trial (NCT07159061) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Philadelphia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced major depressive disorder (mdd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder (mdd) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Philadelphia, PA