Denver, CONCT07284667Now EnrollingIRB Ready

Major Depressive Disorder (MDD) Clinical Trial in Denver, CO

Access cutting-edge major depressive disorder (mdd) treatment through this clinical trial at a research site in Denver. Study-provided care at no cost to qualified participants.

Sponsored by ACADIA Pharmaceuticals Inc.

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Expert Care in Denver

Access major depressive disorder (mdd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder (mdd) treatment provided free

Apply for This Denver Location

Check if you qualify for this major depressive disorder (mdd) clinical trial in Denver, CO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Denver

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Denver site if eligible
  4. 4Begin participation

About This Major Depressive Disorder (MDD) Study in Denver

The goal of this clinical trial is to learn if ACP-211 can help treat adults with major depressive disorder (MDD) who have not improved with antidepressant therapy (ADT), including those with treatment resistant depression (TRD). The main questions the study aims to answer are: * Does ACP-211 work better than a placebo (a look-alike capsule with no medicine) to reduce symptoms of depression? * What adverse events do participants have when taking ACP-211?

Sponsor: ACADIA Pharmaceuticals Inc.

Who Can Participate

Inclusion Criteria

Adults ≥18 and ≤65 years of age
Provides written informed consent
Clinical diagnosis of MDD
History of inadequate response to at least two antidepressants, with at least one inadequate response documented during the current episode
Currently treated with an approved antidepressant at a stable dose prior to Screening
MADRS total score ≥28, CGI-S score ≥4 , and QIDS-SR16 score ≥16 at Screening and Baseline
Females of childbearing potential must have a negative pregnancy test and agree to use acceptable contraception; males must agree to use barrier protection and refrain from sperm donation

Exclusion Criteria

Current diagnosis of certain personality disorders or persistent depressive disorder
Recent substance use disorders, excluding caffeine or nicotine
Active suicidal risk or recent suicidal attempt
History of schizophrenia, psychotic disorders, bipolar disorder, or MDD with psychotic features
Current treatment requirement for PTSD, acute stress disorder, panic disorder, or OCD
History of neuroleptic malignant syndrome, serotonin syndrome, or epilepsy (except single febrile seizure in infancy)
Documented non-response to ADT, including ketamine or esketamine
Allergy or sensitivity to ketamine or esketamine
Significant cardiovascular disease
Positive history of hepatitis B, hepatitis C, or HIV infection
Unstable diabetes or uncontrolled medical conditions
Positive urine drug test for an illicit drug or cannabis
Received neuromodulation therapies (ECT,TMS, VNS, DBS) in the current depressive episode
Recent initiation or change in psychotherapy Additional inclusion/exclusion criteria apply. Participants will be evaluated at Screening to ensure that all criteria for study participation are met.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Denver?

Yes, this clinical trial (NCT07284667) has an active research site in Denver, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder (MDD) Treatment Options in Denver, CO

If you're searching for major depressive disorder (mdd) treatment options in Denver, CO, this clinical trial (NCT07284667) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Denver research site is actively enrolling participants for this clinical trial. You'll receive care from experienced major depressive disorder (mdd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder (mdd) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Denver, CO