Los Angeles, CANCT07294924Now EnrollingIRB Ready

Major Depressive Disorder (MDD) Clinical Trial in Los Angeles, CA

Access cutting-edge major depressive disorder (mdd) treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by Kernel

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Expert Care in Los Angeles

Access major depressive disorder (mdd) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related major depressive disorder (mdd) treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this major depressive disorder (mdd) clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Major Depressive Disorder (MDD) Study in Los Angeles

This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (MDD) at participating clinical sites. A separate cohort of healthy adults will be enrolled as a control group. All data collected in this study are for research purposes only and will not influence clinical decision-making or treatment plans. This study will use TD-fNIRS to measure hemodynamic brain responses at rest and/or during tasks in patients receiving accelerated transcranial magnetic stimulation (TMS). Imaging will occur at multiple timepoints (pre-treatment, post-treatment, and follow-ups). Healthy control participants will complete similar measurements at one visit, with the option for a follow-up visit. The primary objectives are to assess feasibility, characterize brain activity patterns, and explore potential biomarkers associated with treatment response.

Sponsor: Kernel

Who Can Participate

Inclusion Criteria

for: Accelerated TMS cohort
Adults aged 18-75 at the time of enrollment
Primary diagnosis of MDD as defined by the DSM-5
Determined by the clinic to be eligible for accelerated rTMS treatment and agrees to receive accelerated rTMS treatment
Agrees to start accelerated rTMS treatment in conjunction with study participation to capture baseline measurements
Has not received rTMS treatment in the past 1 month
Has not received SPRAVATO treatment in the past 1 month
Can speak and understand English
Ability to provide informed consent Healthy controls cohort
Adults aged 18-75 at time of enrollment
Can speak and understand English
Ability to provide informed consent

Exclusion Criteria

for: All cohorts
Pregnant or may become pregnant during the treatment course
Unable or unwilling to wear the fNIRS headset
Has had electroconvulsive therapy (ECT) in the past 3 months
Major medical illnesses including neurological and psychiatric conditions such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, schizophrenia, or stroke.
Any other clinically significant medical condition that in the opinion of the clinician or study team, could affect patient safety, wellbeing, or the participant's ability to comply with study procedures.
Not an appropriate candidate for the study based on the discretion of the study investigator(s). Healthy controls cohort only
Clinical diagnosis of depression in the past year
Undergoing any treatments for depression in the past year

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT07294924) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Major Depressive Disorder (MDD) Treatment Options in Los Angeles, CA

If you're searching for major depressive disorder (mdd) treatment options in Los Angeles, CA, this clinical trial (NCT07294924) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced major depressive disorder (mdd) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all major depressive disorder (mdd) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA