Richmond, VANCT05424003Now EnrollingIRB Ready

NAFLD Clinical Trial in Richmond, VA

Access cutting-edge nafld treatment through this clinical trial at a research site in Richmond. Study-provided care at no cost to qualified participants.

Sponsored by University of Virginia

Quick Self-Assessment

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Expert Care in Richmond

Access nafld specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related nafld treatment provided free

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Check if you qualify for this nafld clinical trial in Richmond, VA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Richmond

    Convenient for VA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Richmond site if eligible
  4. 4Begin participation

About This NAFLD Study in Richmond

In this study, semaglutide will be compared to placebo (a look-alike inactive substance, a "sugar pill") to determine if its use will prevent weight gain after liver transplantation (LT). In addition, researchers will be testing to determine if semaglutide prevents the development of Non-Alcoholic Fatty Liver Disease (NAFLD) after transplant through Magnetic Resonance Imaging (MRI) and laboratory results.

Sponsor: University of Virginia

Who Can Participate

Inclusion Criteria

Male or female age 18-75 years who received LT for any indication (i.e. NASH, hepatitis C, alcohol-induced cirrhosis, autoimmune hepatitis, etc.)
Liver transplant surgery within 8-24 weeks prior to randomization
Fasting glucose \> 125 mg/dL or presence of diabetes (HbA1c≥6.5% or use of diabetes medications) or pre-diabetes (HbA1c \>5.7%)
Ability to provide informed consent
Discharged from the hospital following LT surgery
Tolerating diet
Normal graft function\
(determined by treating hepatologist/surgeon based on clinical status and hepatic panel)
Stable immunosuppression according the VCU (Virginia Commonwealth University) post-LT protocols \*\
(i.e. calcineurin inhibitors + mycophenolate)
Eligible female patients will be (1) non-pregnant, evidenced by a negative urine pregnancy test, (2) non-lactating, (3)surgically sterile or post-menopausal, or they will agree to continue to use an accepted method of birth control during the study

Exclusion Criteria

BMI≤ 27kg/m2
GFR (Glomerular Filtration Rate) ≤ 25 ml/min/1.73m2
Type 1 autoimmune diabetes (by anti-GAD (glutamic acid decarboxylase) or history of ketoacidosis)
History of gastroparesis
Familial or personal history of medullary thyroid cancer or MEN (Multiple Endocrine Neoplasia) 2
History of pancreatitis
History of active malignancy post- LT with the exception of non-melanoma skin cancers
History of uncontrolled or unstable diabetic retinopathy or maculopathy
Acute cellular rejection
Hepatic artery thrombosis
Medical non-compliance
Active treatment with GLP (glucagon-like peptide)-1RA (receptor agonist) or SGLT (sodium-glucose cotransporter)-2 inhibitors at time of screening
History of hypersensitivity to semaglutide or its excipients
Women who are nursing, pregnant, or planning to become pregnant during the study, or are not using adequate contraceptive measures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Richmond?

Yes, this clinical trial (NCT05424003) has an active research site in Richmond, VA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

NAFLD Treatment Options in Richmond, VA

If you're searching for nafld treatment options in Richmond, VA, this clinical trial (NCT05424003) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Richmond research site is actively enrolling participants for this clinical trial. You'll receive care from experienced nafld specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all nafld clinical trials near you to find additional studies recruiting in your area.

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