Arcadia, CANCT07221227Now EnrollingIRB Ready

Non-alcoholic Fatty Liver Disease Clinical Trial in Arcadia, CA

Access cutting-edge non-alcoholic fatty liver disease treatment through this clinical trial at a research site in Arcadia. Study-provided care at no cost to qualified participants.

Sponsored by GlaxoSmithKline

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Expert Care in Arcadia

Access non-alcoholic fatty liver disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related non-alcoholic fatty liver disease treatment provided free

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Check if you qualify for this non-alcoholic fatty liver disease clinical trial in Arcadia, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Arcadia

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Arcadia site if eligible
  4. 4Begin participation

About This Non-alcoholic Fatty Liver Disease Study in Arcadia

The purpose of this study is to assess the safety and efficacy of efimosfermin alfa in the resolution of steatohepatitis and improvement of liver-related clinical outcome compared to placebo in individuals with MASH and biopsy-confirmed F2- or F3-stage fibrosis.

Sponsor: GlaxoSmithKline

Who Can Participate

Inclusion Criteria

Able and willing to understand and sign a written informed consent form that must be obtained prior to the initiation of study procedures
Age \>=18 and \<=75 years at enrollment
History or presence of 2 or more of the 5 components of metabolic syndrome per American Heart Association definition
Liver biopsy confirmation of MASH consistent with stage F2 or F3 fibrosis and a NAS score \>=4 confirmed by a central pathologist

Exclusion Criteria

Contraindication or ineligibility for percutaneous liver biopsy
ALT or AST \>=5 x upper limit of normal (ULN)
Total bilirubin \>=1.3 milligram per deciliter (mg/dL). Individuals with documented Gilbert's syndrome may be enrolled if they experienced an isolated increase in total bilirubin of \>=1.3 mg/dL and direct bilirubin is \<=20% of total bilirubin; otherwise, the individual will be excluded.
Serum albumin \<=3.5 grams per deciliter (g/dL)
International normalized ratio (INR) \>=1.3 not due to therapeutic anticoagulation. Individuals receiving chronic anticoagulant treatment with higher INR values may be enrolled at the discretion of the Investigator and Study Medical Monitor.
Alkaline phosphatase (ALP) \>=2\*ULN
Platelet (PLT) count \<140,000 per (/) cubic millimeter (mm\^3); individuals with a PLT count between 110,000/mm\^3 and 140,000/mm\^3 may be enrolled after discussion with the Study Medical Monitor.
Serum creatinine \>=1.5 mg/dL or creatinine clearance \<=60 milliliter (mL)/minute (min)/1.73 square meter by Chronic Kidney Disease Epidemiology Collaboration equation
Alpha-fetoprotein \>=20 nanogram per milliliter (ng/mL)
Glycated hemoglobin \>=9.0%
Model for End-Stage Liver Disease score \>=12 unless the score is elevated in the absence of liver dysfunction (e.g., Gilbert's syndrome)
Phosphatidyl ethanol (PEth) \>=80 ng/mL at Screening
Evidence of infection with any of the following:
Human immunodeficiency virus;
Hepatitis B virus (detectable HBsAg at Screening);
Hepatitis C virus (HCV);
Chronic liver disease from any other cause including, but not limited to, alcoholic liver disease; evidence of portal hypertension; viral hepatitis or any history or evidence of cirrhosis on screening liver biopsy; or decompensated liver disease such as clinical ascites, bleeding gastroesophageal varices, hepatorenal syndrome, or hepatic encephalopathy prior to Screening or Day 1.
Current or history of excessive alcohol intake for \>=3 months within the 12-month period prior to Screening

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Arcadia?

Yes, this clinical trial (NCT07221227) has an active research site in Arcadia, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Non-alcoholic Fatty Liver Disease Treatment Options in Arcadia, CA

If you're searching for non-alcoholic fatty liver disease treatment options in Arcadia, CA, this clinical trial (NCT07221227) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Arcadia research site is actively enrolling participants for this clinical trial. You'll receive care from experienced non-alcoholic fatty liver disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all non-alcoholic fatty liver disease clinical trials near you to find additional studies recruiting in your area.

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